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CORC

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1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 448-456
作者:  Jiang, Junhang;  Zhang, Hao;  Wang, Chongqing;  Zhang, Qingsen;  Fang, Shaoyu
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation 期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.168, 页码: 426-435
作者:  Min'an Zhai;  Shiyuan Liu;  Meiqi Gao;  Long Wang;  Jun Sun
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/13
Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 7, 页码: 659-664
作者:  Liu, Guangpu;  Jiao, Yang;  Huang, Chunxi;  Chang, Ping
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site 期刊论文
Bioorganic Chemistry, 2019, 卷号: Vol.85, 页码: 49-59
作者:  Wenlong Li;  Honghao Sun;  Feijie Xu;  Wen Shuai;  Jie Liu
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/13
Synthesis and biological evaluation of 7-methoxy-1-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-benzo[e]indazoles as new colchicine site inhibitors. 期刊论文
Bioorganic and Medicinal Chemistry Letters, 2019, 卷号: 29, 期号: 18, 页码: 2632-2634
作者:  Jiang, Junhang;  Zhang, Qingsen;  Guo, Jiapeng;  Fang, Shaoyu;  Zhou, Ruolan
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/27
The Structure of MT189-Tubulin Complex Provides Insights into Drug Design 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073
作者:  Li, Zhongping;  Ma, Lingling;  Wu, Chengyong;  Meng, Tao;  Ma, Lanping
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy 期刊论文
Journal of Medicinal Chemistry, 2018, 卷号: Vol.61 No.4, 页码: 1704-1718
作者:  Banerjee, S.;  Arnst, K.E.;  Wang, Y.;  Kumar, G.;  Deng, S.
收藏  |  浏览/下载：4/0  |  提交时间：2019/02/25
Synthesis, Molecular Properties Prediction and Biological Evaluation of Indole-Vinyl Sulfone Derivatives as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site 期刊论文
Bioorganic Chemistry, 2018
作者:  Wenlong Li;  Honghao Sun;  Feijie Xu;  Wen Shuai;  Jie Liu
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/26
Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.157, 页码: 1068-1080
作者:  Li, Wenlong;  Yin, Ying;  Yao, Hong;  Shuai, Wen;  Sun, Honghao
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/26
BZML, a novel colchicine binding site inhibitor, overcomes multidrug resistance in A549/Taxol cells by inhibiting P-gp function and inducing mitotic catastrophe 期刊论文
CANCER LETTERS, 2017, 卷号: 402, 页码: 81-92
作者:  Bai, Zhaoshi
收藏  |  浏览/下载：23/0  |  提交时间：2017/10/29

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