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科研机构
西安交通大学 [5]
南华大学 [3]
金属研究所 [2]
大连化学物理研究所 [2]
昆明植物研究所 [2]
上海药物研究所 [1]
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期刊论文 [21]
会议论文 [1]
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2018 [4]
2017 [1]
2016 [1]
2015 [1]
2014 [4]
2013 [3]
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物理化学 [2]
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Role of glycans in cholesteryl ester transfer protein revealed by molecular dynamics simulation
期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 页码: 882-891
作者:
Hao, Dongxiao
;
Yang, Zhiwei
;
Gao, Teng
;
Tian, Zhiqi
;
Zhang, Lei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/11/19
structural modulation
hydrogen bond
CETP
glycosylation
CETP-mediated cholesterol transport
Lipoprotein in cholesterol transport: Highlights and recent insights into its structural basis and functional mechanism
期刊论文
CHINESE PHYSICS B, 2018, 卷号: 27
作者:
Chen, Shu-Yu
;
Li, Na
;
Jin, Tao-Li
;
Gou, Lu
;
Hao, Dong-Xiao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/19
low-density lipoprotein (LDL)
cholesteryl ester transfer protein (CETP)
cholesterol transport
high-density lipoprotein (HDL)
Binding profiles of cholesterol ester transfer protein with current inhibitors: a look at mechanism and drawback
期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2018, 卷号: 36, 页码: 2567-2580
作者:
Yang, Zhiwei
;
Cao, Yang
;
Hao, Dongxiao
;
Yuan, Xiaohui
;
Zhang, Lei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
interaction mechanisms
cholesterol ester transfer protein (CETP)
CETP inhibitors
cardiovascular disease
molecular dynamics
Binding profiles of cholesterol ester transfer protein with current inhibitors: a look at mechanism and drawback
期刊论文
2018, 卷号: 36, 期号: 10, 页码: 2567
作者:
Yang, Zhiwei[1,2]
;
Cao, Yang[1]
;
Hao, Dongxiao[1]
;
Yuan, Xiaohui[3,4]
;
Zhang, Lei[1]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/13
Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc.
期刊论文
CHEMISTRY & BIODIVERSITY, 2017, 卷号: 14, 期号: 1
作者:
Hu, Dongbao
;
Li, Ming
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2017/04/19
Xylaria nigripes
Ergot alkaloids
DFT
CETP Inhibitory activity
Insights into the Tunnel Mechanism of Cholesteryl Ester Transfer Protein through All-atom Molecular Dynamics Simulations
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: [db:dc_citation_issue], 页码: 14034-14044
作者:
Lei, Dongsheng
;
Rames, Matthew
;
Zhang, Xing
;
Zhang, Lei
;
Zhang, Shengli
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/02
cholesterol regulation
lipid-protein interaction
lipoprotein metabolism
lipid metabolism
cholesterol-binding protein
cholesterol
lipid transport
cholesterol metabolism
molecular dynamics
Apolipoprotein M
期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2015, 卷号: 446, 页码: 21-29
作者:
Ren, Kun
;
Tang, Zhen-Li
;
Jiang, Yue
;
Tan, Yan-Mei
;
Yi, Guang-Hui*
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/27
apo
apolipoprotein
HDL
high-density lipoprotein
HNF-1α,4α
hepatocyte nuclear factor-1α,4α
LRH-1
liver receptor homolog-1
Foxa2
forkhead box A2
PAF
platelet activating factor
LXR
liver X receptor
RXR
retinoid X receptor
FXR
farnesoid X receptor
SHP
small heterodimer partner
S1P
Sphingosine-1-Phosphate
CVD
cardiovascular disease
HDL-C
HDL cholesterol
RCT
reverse cholesterol transport
MHC
major histocompatibility complex class III
TNF
tumor necrosis factor
HRP
haptoglobin-related protein
PON-I
paraoxonase-1
SNP
single nucleotide polymorphism
T1,2D
type 1,2 diabetes
RA
rheumatoid arthritis
ABCA1
ATP-binding cassette transporter A1
PPAR-γ
peroxisome proliferator-activated receptor γ
IL
interleukin
ABCG
ATP-binding cassette sub-family G
CETP
cholesteryl ester transfer protein
SR-B1
scavenger receptor class B member 1
MODY3
maturity-onset diabetes of the young type 3
MUP
major urinary protein
RBP
retinol binding protein
RAR
retinoic acid receptor
TR
thyroid hormone receptor
PI3K
phosphatidylinositol 3-kinase
DHC
dihydrocapsaicin
HRE
hormone response element
IGF-1
insulin-like growth factors
PAF-R
platelet activating factor receptor
TGF-α,β
transforming growth factor-α,β
EGF
epidermal growth factor
HGF
hepatic growth factor
VLDL
very low-density lipoprotein
LDL
low-density lipoprotein
ldlr
LDL receptor
ldlr−/−
LDL-receptor deficient
LCAT
lecithin-cholesterol acyltransferase
CE
cholesteryl ester
TC
total cholesterol
LDL-C
LDL cholesterol
VLDL-C
VLDL cholesterol
CHD
coronary heart disease
Mets
metabolic syndrome
S1PR
S1P receptor
NF-κB
nuclear factor-κB
NO
nitrogen oxide
eNOS
endothelial nitric oxide synthase
apoM-TgN mice
mice overexpressing human apoM by approximately two-fold
apoM-TgH mice
mice overexpressing human apoM by approximately ten-fold
apoM−/− mice
apoM-null mice
apoE−/−
apoE-null mice
Apolipoprotein M
Regulation
Function
Relationship between the cholesterol ester transfer protein TaqIB polymorphism and the lipid-lowering effect of atorvastatin in patients with coronary atherosclerotic heart disease
期刊论文
GENETICS AND MOLECULAR RESEARCH, 2014, 卷号: 13, 期号: 1
作者:
Li, J.
;
Zhang, L.
;
Xie, N. Z.
;
Deng, B.
;
Lv, L. X.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Cholesterol ester transfer protein
Gene
Atorvastatin
Coronary artery disease
Association study of promoter polymorphisms in the CETP gene with longevity in the Han Chinese population
期刊论文
Molecular Biology Reports, 2014, 卷号: 41, 期号: X, 页码: 325–329
作者:
Yang JK
;
Gong YY
;
Zhang YP
;
Xie L
;
Yang Y
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2017/03/28
Longevity
CETP
Polymorphisms
Han Chinese population
Pharmacophore-based design, synthesis, and biological evaluation of novel 3-((3,4-dichlorophenyl)(4-substituted benzyl)amino) propanamides as cholesteryl ester transfer protein (CETP) inhibitors
期刊论文
CHINESE CHEMICAL LETTERS, 2014, 卷号: 25, 期号: 2, 页码: 299-304
作者:
Zhao DongMei
;
Li WenYan
;
Shi YuFang
;
Xiong XuQiong
;
Song Shuai
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/02/02
CHIRAL N,N-DISUBSTITUTED TRIFLUORO-3-AMINO-2-PROPANOLS
POTENT INHIBITORS
DISCOVERY
TRANSPORT
Cholesteryl ester transfer protein
CETP inhibitors
Pharmacophore
Virtual screening
Synthesis
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