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上海药物研究所 [2]
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期刊论文 [11]
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Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18, 页码: 17
作者:
Bing, Zhitong
;
Cheng, Zhiyuan
;
Shi, Danfeng
;
Liu, Xinkui
;
Tian, Jinhui
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2019/10/09
Systems pharmacology
Fuzhengkangai formula
Herbal medicines
Molecular docking
Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18
作者:
Bing, Zhitong
;
Cheng, Zhiyuan
;
Shi, Danfeng
;
Liu, Xinkui
;
Tian, Jinhui
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/03/27
Systems pharmacology
Fuzhengkangai formula
Herbal medicines
Molecular docking
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:
Chu, Shifeng
;
Liu, Shaolin
;
Duan, Wenzhen
;
Cheng, Yong
;
Jiang, Xueying
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Chirality
Clausenamide
Dementia
Long-term potentiation
Signaling pathway
Calcium
6-OHDA
6-hydroxyldopamine
ACE
acetylcholinesterase
ACh
acetylcholine
AD
Alzheimer's disease
AUC0–12 h
0–12 h area under curve
APP
amyloid precursor protein
APV
R-2-amino-5-phosphonopentanoate
AUC0−∝
whole area under curve
BBB
blood–brain barrier
BDNF
brain-derived neurotrophic factor
CaM
calmodulin
CaMKII
calmodulin kinase II
ChAT
choline acetyltransferase
CREB
cAMP responding element binding
CHM
Chinese herbal medicine
clau
clausenamide
CL
clearance
Cmax
maximum concentration
CDK-5
cyclin-dependent kinase-5
DM
diabetes mellitus
DAG
diacylglycerol
ER
endoplasmic reticulum
ERK
extracellular signal-regulated kinases
GSK-3
glycogen synthase kinase-3
IP3
inositol triphosphate
LTP
long term potentiation
MWM
Morris water maze
NGF
nerve growth factor
NMDA
N-Methyl-D-aspartate
D
nNOS
neural nitric oxide synthase
PAT
passive avoidance tasks
Pir
piracetam
PLC
phospholipase C
PP1
phosphate 1
PKC
protein kinase C
tmax
time of peak concentration
t1/2α
absorption half-life
t1/2β
elimination half-life
Tau
microtubule-associated proteins
TCM
traditional Chinese medicine
Vd
apparent volume of distribution
VDCC
voltage-dependent calcium channel
Can Chinese Herbal Medicine Adjunctive Therapy Improve Outcomes of Senile Vascular Dementia? Systematic Review with Meta-analysis of Clinical Trials
期刊论文
2015, 卷号: 29, 期号: 12, 页码: 1843-1857
作者:
Zeng, Lingfeng
;
Zou, Yuanping
;
Kong, Lingshuo
;
Wang, Ningsheng
;
Wang, Qi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
senile vascular dementia (SVD)
Chinese herbal medicine (CHM)
adjunctive therapy
systematic review
meta-analysis
randomized controlled trial (RCT)
Metabolic profiling reveals therapeutic biomarkers of processed Aconitum Carmichaeli Debx in treating hydrocortisone induced Kidney-Yang deficiency syndrome rats
期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 3, 页码: 585-593
作者:
Tan, Yong
;
Liu, Xinru
;
Lu, Cheng
;
He, Xiaojuan
;
Li, Jian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
TCM
traditional Chinese medicine
KYDS
Kidney-Yang Deficiency syndrome
HPLC
high-performance liquid chromatography
LC/MS
high-pressure liquid chromatography combined mass spectrometry
LC-Q-TOF-MS
liquid chromatography quadruple time-of-flight mass spectrometry
EIC
extracted ion chromatograms
ESI
electrospray ionization
PCA
principal components analysis
PLS-DA
partial-least-squares discriminate analysis
OPLS
orthogonal partial least square
IPA
ingenuity pathway analysis
cAMP
cyclic adenosine monophosphate
cGMP
cyclic guanosine monophosphate
ACTH
adrenocorticotrophic hormone
CHM
Chinese herbal medicines
Metabolic profiling
Processed Aconitum carmichaeli debx
Therapeutic biomarkers
Kidney-Yang deficiency syndrome rats
Anti-Breast Cancer Agents from Chinese Herbal Medicines
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 1
作者:
You, Lisha
;
An, Rui
;
Liang, Kun
;
Wang, Xinhong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Breast cancer
Chinese herbal medicine(CHM)
herb
natural product
The potential of metabolic fingerprinting as a tool for the modernisation of TCM preparations
期刊论文
journal of ethnopharmacology, 2012, 卷号: 140, 期号: 3, 页码: 482-491
作者:
Sheridan, Helen
;
Krenn, Liselotte
;
Jiang, Renwang
;
Sutherland, Ian
;
Ignatova, Svetlana
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2013/10/11
Chinese herbal medicines
Extraction
Compound analysis
Metabolomics
Fingerprint analysis
Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2012, 卷号: 140, 期号: 3, 页码: 458-468
作者:
Uzuner, Halil
;
Bauer, Rudolf
;
Fan, Tai-Ping
;
Guo, De-An
;
Dias, Alberto
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
GP-TCM
Traditional Chinese medicine
Chinese herbal medicine
Acupuncture
Omics
Guidelines
Study on multiple pesticides by High Performance Liquid Chromatography-Mass Spectrometry using modified QuEChERS method - A case study on CHM
期刊论文
NATURAL RESOURCES AND SUSTAINABLE DEVELOPMENT, PTS 1-3, 2012, 卷号: 361-363, 页码: 1752-1755
作者:
Dong, Yiwei
;
Bai, Wei
;
Li, Yuzhong
;
Xu, Chunying
;
Fang, Fuli
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2016/12/06
QuEChERS
Pesticides
Chinese herbal medicine
HPLC-MS
The herbalome-an attempt to globalize Chinese herbal medicine
期刊论文
analytical and bioanalytical chemistry, 2012, 卷号: 402, 期号: 2, 页码: 573-581
作者:
Zhang, Xiuli
;
Liu, Yanfang
;
Guo, Zhimou
;
Feng, Jiatao
;
Dong, Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2015/11/12
Herbalome
TCM
Chinese herbal medicine
Separation technique
Fine multi-components
Sample library
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