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上海药物研究所 [14]
复旦大学上海医学院 [5]
中国医学科学院 北京... [5]
大连化学物理研究所 [4]
上海中医药大学 [2]
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期刊论文 [26]
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Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate
期刊论文
DRUG METABOLISM AND DISPOSITION, 2018, 卷号: 46, 期号: 9, 页码: 1320-1328
作者:
Hou, Xiangyu
;
Zhou, Jialan
;
Yu, Songda
;
Zhou, Lei
;
Zhang, Yifan
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
Direct and quantitative evaluation of the major human CYP contribution (fmCYP) to drug clearance using the in vitro Silensomes™ model
期刊论文
Xenobiotica; the fate of foreign compounds in biological systems, 2018, 页码: 1-14
作者:
Parmentier, Yannick
;
Pothier, Corinne
;
Hewitt, Nicola
;
Vincent, Ludwig
;
Caradec, Fabrice
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Prediction of Drug-Drug Interactions with Bupropion and Its Metabolites as CYP2D6 Inhibitors Using a Physiologically-Based Pharmacokinetic Model
期刊论文
PHARMACEUTICS, 2018, 卷号: 10, 期号: 1
作者:
Xue, Caifu
;
Zhang, Xunjie
;
Cai, Weimin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
physiologically based pharmacokinetic model
drug-drug interactions
bupropion
hydroxybupropion
threohydrobupropion
erythrohydrobupropion
inhibitory metabolites
CYP2D6*10 genotype was associated with worse outcome of premenopausal breast cancer patients receiving adjuvant tamoxifen but not toremifene: A single institution expericence
会议论文
CANCER RESEARCH, 2018-02-01
作者:
Lan, Bo
;
Ma, Fei
;
Fan, Ying
;
Zhai, Xiaoyu
;
Xu, Binghe
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
CYP2D6*10 genotype was associated with worse outcome of premenopausal breast cancer patients receiving adjuvant tamoxifen but not toremifene: A single institution expericence
期刊论文
2018, 卷号: 78, 期号: 4
作者:
Lan, Bo
;
Ma, Fei
;
Fan, Ying
;
Zhai, Xiaoyu
;
Xu, Binghe
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Toremifene, rather than tamoxifen, might be a better option for the adjuvant endocrine therapy in CYP2D6*10T/T genotype breast cancer patients in China
期刊论文
2018, 卷号: 143, 期号: 10, 页码: 2499-2504
作者:
Lan, Bo
;
Ma, Fei
;
Chen, Shanshan
;
Wang, Wenna
;
Li, Qiao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
breast cancer
TAM
TOR
CYP2D6
SNP
Metabolic profiling of five flavonoids from Dragon's Blood in human liver microsomes using high-performance liquid chromatography coupled with high resolution mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2017, 卷号: 1052, 页码: 91-102
作者:
Li, Yujuan
;
Zhang, Yushi
;
Wang, Rui
;
Wei, Lizhong
;
Deng, Yulin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2018/04/10
Dragon's Blood
Human Liver Microsomes
Hplc-hr-ms
Metabolites
The effect of CYP2D6*10 polymorphism on adjuvant tamoxifen in Asian breast cancer patients: a meta-analysis
期刊论文
ONCOTARGETS AND THERAPY, 2017, 卷号: 10
作者:
Lu, Junjun
;
Li, He
;
Guo, Peng
;
Shen, Rui
;
Luo, Yingbin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
CYP2D6*10
polymorphism
breast cancer
Asia
tamoxifen adjuvant treatment
CYP2D6 Phenotyping Using Urine, Plasma, and Saliva Metabolic Ratios to Assess the Impact of CYP2D6(∗)10 on Interindividual Variation in a Chinese Population
期刊论文
2017, 卷号: 8, 页码: 239
作者:
Chen Rui
;
Zheng Xin
;
Hu Pei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
CYP2D6∗10
genotype
metabolic ratio
phenotyping method
polymorphism
Effects of the Chinese herbal formula "Zuojin Pill" on the pharmacokinetics of dextromethorphan in healthy Chinese volunteers with CYP2D6*10 genotype
期刊论文
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2016, 卷号: 72, 期号: 6
作者:
Qiu, Furong
;
Liu, Songcan
;
Miao, Ping
;
Zeng, Jin
;
Zhu, Leilei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
CYP2D6*10 genotype
Zuojin Pill
Drug interaction
Dextromethorphan
Pharmacokinetics
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