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浏览/检索结果: 共5条，第1-5条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595 作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 PRC2  EZH2-EED  AZD9291  miR-34a  non-canonical base pairing   Using CETSA assay and a mathematical model to reveal dual Bcl-2/Mcl-1 inhibition and on-target mechanism for ABT-199 and S1 期刊论文 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, 卷号: 142, 页码: 105105 作者:  Guo Zongwei;  Song Ting;  Xue Zuguang;  Liu Peng;  Zhang Minhang 收藏  |  浏览/下载：18/0  |  提交时间：2019/12/02 BH3 mimetics,Bcl-2 family proteins,CETSA,Mathematical modelling   Design, synthesis and pharmacological evaluation of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-N-arylmethyl-1,2,3,4-tetrahydro-3- isoquinolinecarboxamides as potent Hsp90 inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 143, 页码: 85-96 作者:  Liang, Chuanpeng;  Wu, Xingkang;  Li, Zhenyu;  Zhu, Jing;  Lu, Chunhua 收藏  |  浏览/下载：14/0  |  提交时间：2019/12/11 Hsp90 inhibitors  CETSA  Molecular dynamics simulation  Apoptosis  IKK   CDDO-Me reveals USP7 as a novel target in ovarian cancer cells 期刊论文 Oncotarget, 2016, 卷号: 7, 期号: 47, 页码: 77096-77109 作者:  Qin, Dongjun;  Wang, Weiwei;  Lei, Hu;  Luo, Hao;  Cai, Haiyan 收藏  |  浏览/下载：40/0  |  提交时间：2017/02/14 CDDO-Me  ovarian cancer  USP7  CETSA  deubiquitinating enzymes   Design and synthesis of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-1,2,3,4-tetrahydroisoquinoline-3-c arboxamidesas novel Hsp90 inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 121, 页码: 272-282 作者:  Liang, Chuanpeng;  Hao, Huilin;  Wu, Xingkang;  Li, Zhenyu;  Zhu, Jing 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/16 Design and synthesis  Hsp90 inhibitors  CETSA  Molecular dynamics  simulation