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科研机构
上海药物研究所 [10]
大连化学物理研究所 [2]
复旦大学上海医学院 [1]
内容类型
期刊论文 [12]
会议论文 [1]
发表日期
2019 [1]
2018 [1]
2016 [9]
2015 [1]
2010 [1]
学科主题
物理化学 [1]
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Simultaneous determination of cinobufagin and its five metabolites in rat plasma by LC-MS/MS for characterization of metabolic profiles and pharmacokinetic study
期刊论文
ANALYTICAL METHODS, 2019, 卷号: 11, 期号: 42, 页码: 5464-5471
作者:
Wei, Wenlong
;
Li, Haojv
;
Li, Zhenwei
;
Qu, Hua
;
Da, Juan
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway
期刊论文
International immunopharmacology, 2018, 卷号: 64, 页码: 24-32
作者:
Wu, Xiao-Yu
;
Tian, Fang
;
Su, Min-Hui
;
Wu, Min
;
Huang, Yue
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Knockdown of Apolipoprotein E Enhanced Sensitivity of Hep3B Cells to Cardiac Steroids via Regulating Na+/K+-ATPase Signalosome
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2016, 卷号: 15, 期号: 12, 页码: 2955-2965
作者:
Liu, Miao
;
Feng, Li-Xing
;
Sun, Peng
;
Liu, Wang
;
Mi, Tian
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
A Novel Bufalin Derivative Exhibited Stronger Apoptosis-Inducing Effect than Bufalin in A549 Lung Cancer Cells and Lower Acute Toxicity in Mice
期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 7
作者:
Liu, Miao
;
Feng, Li-Xing
;
Sun, Peng
;
Liu, Wang
;
Wu, Wan-Ying
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
Inhibitory efficacy of bufadienolides on Na,K-pump activity versus cell proliferation
期刊论文
Biochemistry and biophysics reports, 2016, 卷号: 6, 页码: 158-164
作者:
Xu, Yinfang
;
Liu, Xuan
;
Schwarz, Silvia
;
Hu, Lihong
;
Guo, Dean
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  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibiting beta 1 subunit expression and disrupting proteasome assembly
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 7, 页码: 908-918
作者:
Sun, Peng
;
Feng, Li-xing
;
Zhang, Dong-mei
;
Liu, Miao
;
Liu, Wang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
bufalin
ChanSu
cardiac steroids
proteasome beta 1 subunit
proteasome assembly
A549 human lung cancer cells
proteomics
Synthesis and biological evaluation of bufalin-3-yl nitrogen-containing-carbamate derivatives as anticancer agents
期刊论文
STEROIDS, 2016, 卷号: 108, 页码: 56-60
作者:
Lei, Min
;
Xiao, Zhiyong
;
Ma, Biao
;
Chen, Yijia
;
Liu, Miao
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/01/08
Cardiac glycosides
Bufalin (BF)
Natural product
Bufalin-3-yl carbamate
Cytotoxicity
Possible target-related proteins and signal network of bufalin in A549 cells suggested by both iTRAQ-based and label-free proteomic analysis
期刊论文
PROTEOMICS, 2016, 卷号: 16, 期号: 6, 页码: 935-945
作者:
Zhang, Dong-Mei
;
Feng, Li-Xing
;
Liu, Miao
;
Jin, Wen-Hai
;
Luo, Ji
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
A549 cells
Bufalin
Cell biology
iTRAQ-based
Label-free
Inhibitory efficacy of bufadienolides on Na+,K+-pump activity versus cell proliferation.
期刊论文
Biochemistry and biophysics reports, 2016, 卷号: 6
作者:
Xu Yinfang
;
Liu Xuan
;
Schwarz Silvia
;
Hu Lihong
;
Guo Dean
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
BAP, Bufalin-3-MeON-arabinopyranoside
BF238, Bufalin-3-Yl [3-(1h-imidazol-1-Yl)propyl]carbamate
BF601, Bufalin-3-Yl [3-(methylamino)propyl]carbamate
Bufadienolide
Cell proliferation
MTT, 3,[4,5-dimethylthiazol-2-Yl-] diphenyltetrazolium bromide
Na+,K+-ATPase
ORi, Oocyte Ringer's (solution)
Rα1/β1, rat Na+,K+pump formed by Α1 and Β1 subunits
Rα2/β1, rat Na+,K+pump formed by Α2 and Β1 subunits
TEA‐Cl, Tetraethylammonium chloride
Voltage clamp
Xenopus oocyte
bufalinderivativebf211inhibitsproteasomeactivityinhumanlungcancercellsinvitrobyinhibiting1subunitexpressionanddisruptingproteasomeassembly
期刊论文
actapharmacologicasinica, 2016, 卷号: 000, 期号: 007, 页码: 908
作者:
Pengsun
;
Feng Lixing
;
Zhang Dongmei
;
Liu Miao
;
Liu Wang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
26S蛋白酶体
肺癌细胞
活性肽
衍生物
亚基
体外抑制
蟾酥
A549细胞
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