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科研机构
上海药物研究所 [3]
中国医学科学院 北京... [2]
四川大学 [1]
暨南大学 [1]
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期刊论文 [7]
发表日期
2017 [4]
2013 [1]
1998 [1]
1995 [1]
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Anti-inflammatory and protective effects of MT-031, a novel multitarget MAO-A and AChE/BuChE inhibitor in scopolamine mouse model and inflammatory cells
期刊论文
2017, 卷号: 113, 期号: [db:dc_citation_issue], 页码: 445
作者:
Liu, Wei[1]
;
Rabinovich, Alon[2]
;
Nash, Yuval[2,4]
;
Frenkel, Dan[2,4]
;
Wang, Yuqiang[3]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
Novel Ferulic Acid-donepezil Hybrids as Multifunctional Agents for th e Treatment of Alzheimer’s Disease with Butyrylcholinesterase, Amyloid- β, Antioxidant and Neuroprotective Properties
期刊论文
Letters in Drug Design & Discovery, 2017, 卷号: Vol.14 No.8, 页码: 918-929
作者:
Tianping Li
;
Wanli Pan
;
Keren Wang
;
Wenmin Liu
;
Qianwen Ma and Zhipei Sang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/02/25
Alzheimer\'s disease
ferulic acid-donepezil hybrids
antioxidant activity
BuChE inhibitor
Aβ aggregation
neuroprotective effects
blood-brain barrier.
Discovery of novel isoflavone derivatives as AChE/BuChE dual-targeted inhibitors: synthesis, biological evaluation and molecular modelling
期刊论文
2017, 卷号: 32, 期号: 1, 页码: 968-977
作者:
Feng, Bo
;
Li, Xinpeng
;
Xia, Jie
;
Wu, Song
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
Alzheimer's disease
isoflavone derivatives
AChE/BuChE dual-targeted inhibitor
molecular modelling
DL0410 Ameliorates Memory and Cognitive Impairments Induced by Scopolamine via Increasing Cholinergic Neurotransmission in Mice
期刊论文
2017, 卷号: 22, 期号: 3
作者:
Lian, Wenwen
;
Fang, Jiansong
;
Xu, Lvjie
;
Zhou, Wei
;
Kang, De
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
Alzheimer's disease
DL0410
AChE inhibitor
BuChE inhibitor
ACh
Discovery of novel 2,6-disubstituted pyridazinone derivatives as acetylcholinesterase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 63, 页码: 95-103
作者:
Xing, Weiqiang
;
Fu, Yan
;
Shi, Zhangxing
;
Lu, Dong
;
Zhang, Haiyan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Pyridazinone
Acetylcholinesterase
Alzheimer's disease
Docking study
Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities
期刊论文
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1998, 卷号: 60, 期号: 2, 页码: 377-386
作者:
Cheng, DH
;
Tang, XC
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/01/08
Alzheimer's disease
cholinesterase inhibitor
huperzine A
E2020
tacrine
rat radial maze
learning and memory
cholinesterase
EFFECTS OF ISOVANIHUPERZINE-A ON CHOLINESTERASE AND SCOPOLAMINE-INDUCED MEMORY IMPAIRMENT
期刊论文
ACTA PHARMACOLOGICA SINICA, 1995, 卷号: 16, 期号: 1, 页码: 21-25
作者:
XIONG, ZQ
;
TANG, XC
;
LIN, JL
;
ZHU, DY
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
HUPERZINE A
ISOVANIHUPERZINE A
PHYSOSTIGMINE
GALANTHAMINE
CHOLINESTERASE INHIBITORS
SCOPOLAMINE
ISOFLUROPHATE
COGNITION DISORDERS
MEMORY
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