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Characterization of the metabolites of tirabrutinib generated from rat, dog and human liver microsomes using ultra-high-performance liquid chromatography combined with high-resolution mass spectrometry 期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2022, 卷号: 36
作者:  Zhang, Hongjian;  Hu, Zhen;  Zhang, Huiping;  Sun, Xiyan;  Yang, Jianming
收藏  |  浏览/下载:41/0  |  提交时间:2022/03/28
Bruton's tyrosine kinase inhibitors in primary central nervous system lymphoma-evaluation of anti-tumor efficacy and brain distribution 期刊论文
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:  Yu, Haifeng;  Kong, Haiying;  Li, Cong;  Dong, Xiaowu;  Wu, Yizhe
收藏  |  浏览/下载:24/0  |  提交时间:2021/08/31
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:  Liu, Yu-ting;  Ding, Hui-hua;  Lin, Ze-min;  Wang, Que;  Chen, Li
收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24
Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2 期刊论文
BLOOD ADVANCES, 2021, 卷号: 5, 期号: 1, 页码: 185-197
作者:  Wu, Wenjun;  Wang, Weige;  Franzen, Carrie A.;  Guo, Hui;  Lee, Jimmy
收藏  |  浏览/下载:42/0  |  提交时间:2020/07/01
Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5
作者:  Liu, Juan;  Liang, Qianmao;  Wang, Aoli;  Zou, Fengming;  Qi, Ziping
收藏  |  浏览/下载:18/0  |  提交时间:2020/11/30
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:  Zhang, Xiao-tuan;  Hu, Xiao-bei;  Wang, Han-lin;  Kan, Wei-juan;  Xu, Lei
收藏  |  浏览/下载:49/0  |  提交时间:2020/12/24
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/01
discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415
作者:  Lai Mengzhen;  Song Peiran;  Dou Dou;  Diao Yanyan;  Tong Linjiang
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/01
Analysis of Four Types of Leukemia Using Gene Ontology Term and Kyoto Encyclopedia of Genes and Genomes Pathway Enrichment Scores 期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2020, 卷号: 23, 期号: 4, 页码: 295-303
作者:  Lu, Jing;  Zhang, YuHang;  Wang, ShaoPeng;  Bi, Yi;  Huang, Tao
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/01
Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395
作者:  Diao, Yanyan;  Fang, Xiaoyu;  Song, Peiran;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/01


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