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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载:5/0  |  提交时间:2024/04/07
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:  Lu, Tingting;  Cao, Jiangyan;  Zou, Fengming;  Li, Xixiang;  Wang, Aoli
收藏  |  浏览/下载:42/0  |  提交时间:2021/04/26
Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells 期刊论文
ANTIOXIDANTS, 2019, 卷号: 8, 期号: 9
作者:  Lu, Xuxiu;  Geng, Jiajia;  Zhang, Jinman;  Miao, Jinlai;  Liu, Ming
收藏  |  浏览/下载:32/0  |  提交时间:2019/10/29
Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells 期刊论文
ANTIOXIDANTS, 2019, 卷号: 8, 期号: 9
作者:  Lu, Xuxiu;  Geng, Jiajia;  Zhang, Jinman;  Miao, Jinlai;  Liu, Ming
收藏  |  浏览/下载:30/0  |  提交时间:2019/10/29
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
收藏  |  浏览/下载:29/0  |  提交时间:2019/11/27
Natural products as important tyrosine kinase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 111664
作者:  Yin, Bo;  Fang, Dong-Mei;  Zhou, Xian-Li;  Gao, Feng
收藏  |  浏览/下载:18/0  |  提交时间:2021/11/04
Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 122-132
作者:  Liu, Yang;  Peng, Xia;  Guan, Xiaocong;  Lu, Dong;  Xi, Yong
收藏  |  浏览/下载:42/0  |  提交时间:2019/01/08
Discovery of 4-Methyl-N-(44(4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((1-nicotinoylpiperidin-4-y1)oxy)benzamide (CHMFL-ABL/KIT-155) as a Novel Highly Potent Type II ABL/KIT Dual Kinase Inhibitor with a Distinct Hinge Binding 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 1, 页码: 273-289
作者:  Wang, Qiang;  Liu, Feiyang;  Wang, Beilei;  Zou, Fengming;  Qi, Ziping
收藏  |  浏览/下载:29/0  |  提交时间:2018/07/04
Analysis of clinical characteristics and efficacy of chronic myeloid leukemia onset with extreme thrombocytosis in the era of tyrosine kinase inhibitors 期刊论文
ONCOTARGETS AND THERAPY, 2017, 卷号: 10
作者:  Liu, Zhihe;  Fan, Hongqiong;  Li, Yuying;  Liu, Chunshui
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/05
基于Dasatinib的酪氨酸激酶小分子抑制剂的设计、合成及生物活性研究 学位论文
广州生物院: 中国科学院大学, 2016
作者:  刘露
收藏  |  浏览/下载:52/0  |  提交时间:2018/12/25


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