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High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer 期刊论文
BREAST CANCER, 2021
作者:  Zhu, Liang;  Pan, Jia-Ni;  Qian, Ziliang;  Ye, Wei-Wu;  Wang, Xiao-Jia
收藏  |  浏览/下载:23/0  |  提交时间:2021/09/06
CIN  TP53  BRCA1  LPWGS  Breast cancer  
DAGM: A novel modelling framework to assess the risk of HER2-negative breast cancer based on germline rare coding mutations 期刊论文
EBIOMEDICINE, 2021, 卷号: 69, 页码: 11
作者:  Yang, Mei;  Fan, Yanhui;  Wu, Zhi-Yong;  Gu, Jin;  Feng, Zhendong
收藏  |  浏览/下载:44/0  |  提交时间:2021/12/01
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong
收藏  |  浏览/下载:11/0  |  提交时间:2020/12/24
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong
收藏  |  浏览/下载:49/0  |  提交时间:2020/12/24
Evaluation of the BRCAness phenotype and its correlations with clinicopathological features in triple-negative breast cancers 期刊论文
HUMAN PATHOLOGY, 2019, 卷号: 84
作者:  Tian, Tian;  Shan, Ling;  Yang, Wentao;  Zhou, Xiaoyan;  Shui, Ruohong
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/05
Multiple cancer susceptible genes sequencing in BRCA-negative breast cancers with high hereditary risk 会议论文
作者:  Lang, G-T;  Hu, X.;  Shao, Z-M;  Huang, W.;  Shi, J-X
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/05
Patient-reported outcomes in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer receiving olaparib versus chemotherapy in the OlympiAD trial 期刊论文
2019, 卷号: 120, 页码: 20-30
作者:  Robson Mark;  Ruddy Kathryn J;  Im Seock-Ah;  Senkus Elżbieta;  Xu Binghe
收藏  |  浏览/下载:21/0  |  提交时间:2020/01/03
OlympiAD final overall survival and tolerability results: Olaparib versus chemotherapy treatment of physician's choice in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer 期刊论文
2019, 卷号: 30, 期号: 4, 页码: 558-566
作者:  Robson, M. E.;  Tung, N.;  Conte, P.;  Im, S-A;  Senkus, E.
收藏  |  浏览/下载:8/0  |  提交时间:2020/01/03
Subgroup analysis of olaparib monotherapy versus chemotherapy by hormone receptor and BRCA mutation status in patients with HER2-negative metastatic breast cancer and a germline BRCA mutation: OlympiAD 会议论文
作者:  Senkus-Konefka, E.;  Domchek, S. M.;  Im, S. A.;  Xu, B.;  Armstrong, A.
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/05
Tolerability of olaparib monotherapy versus chemotherapy in patients with HER2-negative metastatic breast cancer and a germline BRCA mutation: OlympiAD 期刊论文
CANCER RESEARCH, 2018, 卷号: 78, 期号: 4
作者:  Domchek, Susan M.;  Robson, Mark;  Im, Seock-Ah;  Senkus, Elzbieta;  Xu, Binghe
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05


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