×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [14]
复旦大学上海医学院 [4]
山东大学 [3]
上海生物化学与细胞生... [2]
湖南大学 [2]
西安交通大学 [1]
更多...
内容类型
期刊论文 [31]
会议论文 [1]
发表日期
2022 [1]
2019 [4]
2018 [10]
2017 [5]
2016 [3]
2014 [2]
更多...
学科主题
Science & ... [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共32条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Treatment outcomes and prognosis of patients with primary and acquired BRAF-mutated non-small cell lung cancer: A multicenter retrospective study
期刊论文
GENES CHROMOSOMES & CANCER, 2022
作者:
Wang, Wenxian
;
Gu, Xiaodong
;
Si, Jinfei
;
Pu, Xingxiang
;
Wang, Liping
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/05/16
BRAF mutation
immune checkpoint inhibitors
non-small cell lung cancer
PD-L1
targeted therapy
MAPK Inhibitors Enhance HDAC Inhibitor-Induced Redifferentiation in Papillary Thyroid Cancer Cells Harboring BRAF(V600E) : An In Vitro
期刊论文
MOLECULAR THERAPY-ONCOLYTICS, 2019, 卷号: 12
作者:
Cheng, Lingxiao
;
Cheng, Lin
;
Liu, Min
;
Chen, Libo
;
Fu, Hao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: Vol.40 No.2, 页码: 268-278
作者:
Gao, Ming-zhao
;
Wang, Hong-bin
;
Chen, Xiang-ling
;
Cao, Wen-ting
;
Fu, Li
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/13
BRAF-mutant melanoma
MAPK pathway inhibitors
acquired resistance
P70S6K
RSK
rpS6
G(1)/G(0) phase arrest
mTOR inhibitor
A high-performance liquid chromatography-tandem mass spectrometry method for the determination of lifrafenib, a novel RAF kinase and EGFR inhibitor, in human plasma and urine and its application in clinical pharmacokinetic study
期刊论文
2019, 卷号: 166, 页码: 20-29
作者:
Yao, Xueting
;
Song, Ling
;
Liu, Yang
;
Wang, Huanhuan
;
Liu, Jie
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
HPLC-MS/MS
Pharmacokinetics
BRAF V600E
EGFR
Lifirafenib
aberrantmodulationofribosomalproteins6phosphorylationconfersacquiredresistancetomapkpathwayinhibitorsinbrafmutantmelanoma
期刊论文
中国药理学报英文版, 2019, 卷号: 040, 期号: 002, 页码: 268
作者:
Mingzhao Gao
;
Hongbin Wang
;
Xiangling Chen
;
Wenting Cao
;
Li Fu
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
BRAF-mutant
melanoma
MAPK
pathway
inhibitors
acquired
resistance
P70S6K
RSK
rpS6
G1/G0
phase
arrest
mTOR
inhibitor
Identification of recurrent USP48 and BRAF mutations in Cushing's disease
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:
Chen, Jianhua
;
Jian, Xuemin
;
Deng, Siyu
;
Ma, Zengyi
;
Shou, Xuefei
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2019/01/08
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:
Liu, Feifei
;
Yang, Xiaotong
;
Geng, Meiyu
;
Huang, Min
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Mitogen-activated protein kinases
Extracellular signal-regulated kinase
ERK inhibitor
ERK kinase
Cancer therapy
Drug resistance
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Gao, Ming-Zhao
;
Wang, Hong-Bin
;
Chen, Xiang-Ling
;
Cao, Wen-Ting
;
Fu, Li
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
BRAF and EGFR inhibitors synergize to increase cytotoxic effects and decrease stem cell capacities in BRAF(V600E)-mutant colorectal cancer cells
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 4
作者:
Wu, Zhenhua
;
Huang, Mingzhu
;
Gong, Yiwei
;
Lin, Chen
;
Guo, Weijian
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
BRAF inhibitor
dabrafenib
cetuximab
colorectal cancer
cancer stem cells
Discovery of 2-(aminopyrimidin-5-yl)-4-(morpholin-4-yl)-6- substituted triazine as PI3K and BRAF dual inhibitor.
期刊论文
Future medicinal chemistry, 2018, 卷号: 10, 页码: 2445-2455
作者:
Wang Hui-Yan
;
Shen Ying
;
Zhang Hao
;
Hei Yuan-Yuan
;
Zhao Hong-Yi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/19
BRAF inhibitor
drug design
PI3K inhibitor
antiproliferative effects
PI3K and BRAF dual inhibitor
©版权所有 ©2017 CSpace - Powered by
CSpace