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Energy restriction causes metaphase delay and chromosome mis-segregation in cancer cells
期刊论文
CELL CYCLE, 2021, 页码: 14
作者:
Cheng, Aoxing
;
Jiang, Ya
;
Wang, Ting
;
Yu, Fazhi
;
Ishrat, Iqra
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/01
ATP
energy restriction
cancer cells
metaphase-anaphase transition
chromosome mis-segregation
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:
Chen, Jingjing
;
Li, Yalei
;
Zhang, Jie
;
Zhang, Minmin
;
Wei, Aihuan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
HDAC
BRD4
Selective dual inhibitors
Anticancer
Design, synthesis and bioactivity study of evodiamine derivatives as multifunctional agents for the treatment of hepatocellular carcinoma
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114
作者:
Fan, Xiaohong
;
Deng, Jiedan
;
Shi, Tao
;
Wen, Huaixiu
;
Li, Junfang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/11/18
Hepatocellular carcinoma
Topo I
Evodiamine
Cancer-associated fibroblasts (CAFs)
Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:
Ma, Liying
;
Bian, Xing
;
Lin, Wenchu
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  |  
浏览/下载:38/0
  |  
提交时间:2020/11/30
SCLC
PI3K
HDAC
CUDC-907
PARP1
Olaparib
DSB repair
Combination treatment
Radiosensitization of NSCLC cells to X-rays and carbon ions by the CHK1/CHK2 inhibitor AZD7762, Honokiol and Tunicamycin
期刊论文
RADIATION AND ENVIRONMENTAL BIOPHYSICS, 2020, 页码: 10
作者:
Liu, Bingtao
;
Chen, Weiqiang
;
Li, Hongbin
;
Li, Feifei
;
Jin, Xiaodong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/15
Radiosensitivity
X-rays
Carbon ions
AZD7762
Honokiol
Tunicamycin
Harnessing the targeting potential of differential radiobiological effects of photon versus particle radiation for cancer treatment
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2020, 页码: 17
作者:
Zhang, Jinhua
;
Si, Jing
;
Gan, Lu
;
Zhou, Rong
;
Guo, Menghuan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/01/12
DNA damage
DNA repair
particle therapy
photon therapy
radiosensitizer
Protein Palmitoylation Regulates Cell Survival by Modulating XBP1 Activity in Glioblastoma Multiforme
期刊论文
MOLECULAR THERAPY-ONCOLYTICS, 2020, 卷号: 17
作者:
Chen, Xueran
;
Li, Hao
;
Fan, Xiaoqing
;
Zhao, Chenggang
;
Ye, Kaiqin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/10/26
Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1)
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 195, 页码: 13
作者:
Zhang, Shiyan
;
Huang, Chaoying
;
Lyu, Xilin
;
Wang, Peipei
;
Zang, Yi
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
ASK1
ASK2
Selectivity
Apoptosis
Cell cycle arrest
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:
Xi, Mengyu
;
He, Wan
;
Li, Bo
;
Zhou, Jinfeng
;
Xu, Zhijian
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/12/24
DCZ0801
DLBCL
apoptosis
cell cycle
MAPK
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