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科研机构
复旦大学上海医学院 [9]
上海药物研究所 [3]
过程工程研究所 [2]
兰州大学 [1]
山东大学 [1]
华南理工大学 [1]
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期刊论文 [21]
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2019 [2]
2018 [5]
2017 [3]
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Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease
期刊论文
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
作者:
Huang, Ya-ru
;
Xie, Xi-xiu
;
Ji, Mei
;
Yu, Xiao-lin
;
Zhu, Jie
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/04/03
Parkinson's disease
alpha-Synuclein
Naturally occurring autoantibodies
A53T mice
WIG
Resveratrol alleviates motor and cognitive deficits and neuropathology in the A53T-synuclein mouse model of Parkinson's disease
期刊论文
FOOD & FUNCTION, 2018, 卷号: 9, 期号: 12, 页码: 6415-6427
作者:
Zhang, Li-fan
;
Yu, Xiao-lin
;
Ji, Mei
;
Liu, Shu-ying
;
Wu, Xiao-ling
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/04/03
Ginkgolide K promotes the clearance of A53T mutation alpha-synuclein in SH-SY5Y cells
期刊论文
CELL BIOLOGY AND TOXICOLOGY, 2018, 卷号: 34, 期号: 4
作者:
Yu, Wenbo
;
Chen, Sheng
;
Cao, Liang
;
Tang, Jie
;
Xiao, Wei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Alpha-synuclein
Ginkgolide B
Ginkgolide K
Autophagy
Genomic DNA levels of mutant alpha-synuclein correlate with non-motor symptoms in an A53T Parkinson's disease mouse model
期刊论文
NEUROCHEMISTRY INTERNATIONAL, 2018, 卷号: 114
作者:
Wang, Weiwei
;
Song, Ning
;
Jia, Fengjv
;
Tang, Tingting
;
Bao, Weiqi
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
A53T mice
Parkinson's disease
Alpha-synuclein
Non-motor symptoms
Dopamine transporter
Silencing of Glucocerebrosidase Gene in Drosophila Enhances the Aggregation of Parkinson's Disease Associated alpha-Synuclein Mutant A53T and Affects Locomotor Activity
期刊论文
FRONTIERS IN NEUROSCIENCE, 2018, 卷号: 12
作者:
Khair, Salema B. Abul
;
Dhanushkodi, Nisha R.
;
Ardah, Mustafa T.
;
Chen, Wenfeng
;
Yang, Yufeng
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/11/21
neurodegeneration
Drosophila
GBA
sleep behavior
synuclein
Parkinson's disease
RTP801 is a critical factor in the neurodegeneration process of A53T alpha-synuclein in a mouse model of Parkinson's disease under chronic restraint stress.
期刊论文
British Journal of Pharmacology, 2018, 卷号: 175, 期号: 4, 页码: 590-605
作者:
Zhang, Zhao
;
Chu, Shi-Feng
;
Wang, Sha-Sha
;
Jiang, Yi-Na
;
Gao, Yan
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/27
Nuclear Accumulation of Histone Deacetylase 4 (HDAC4) Exerts Neurotoxicity in Models of Parkinson's Disease
期刊论文
MOLECULAR NEUROBIOLOGY, 2017, 卷号: 54, 期号: 9, 页码: 6970-6983
作者:
Wu, Qimei
;
Yang, Xiaoyu
;
Zhang, Lei
;
Zhang, Yu
;
Feng, Linyin
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
HDAC4
alpha-Synuclein
Neuroprotection
Parkinson's disease
PKC
Trehalose Inhibits A53T Mutant alpha-Synuclein Overexpression and Neurotoxicity in Transduced PC12 Cells
期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 8
作者:
Pan, Luanfeng
;
Zhao, Juan
;
Zhi, Xiuling
;
Zhou, Ping
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
alpha-synuclein
trehalose
transduced PC12 cell
Parkinson's disease
MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian
期刊论文
ONCOTARGET, 2017, 卷号: 8, 页码: 15-28
作者:
Mo, Mingshu[1]
;
Xiao, Yousheng[2]
;
Huang, Shuxuan[1]
;
Cen, Luan[2]
;
Chen, Xiang[2]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/24
Parkinson's disease
A53T mutation
microRNAs
deep sequencing
Gerotarget
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