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科研机构
中国医学科学院 北... [29]
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期刊论文 [29]
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2019 [6]
2018 [5]
2017 [7]
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专题:中国医学科学院 北京协和医学院
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Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction
期刊论文
2019, 卷号: 24, 期号: 15
作者:
Lin Wei
;
Zhuang Cangwei
;
Hu Xiuxiu
;
Zhang Juanjuan
;
Wang Juxian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
coumarin
pyrazolo[3
4-b]pyridine
silica sulfuric acid
synthesis
Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis
期刊论文
2019, 卷号: 5, 期号: 7, 页码: 1087-1104
作者:
Wu, Jie
;
Mu, Ran
;
Sun, Mingna
;
Zhao, Nan
;
Pan, Miaomiao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
agrimophol
diphenylmethane scaffold
Mycobacterium tuberculosis
intrabacterial pH homeostasis
coumarin
pharmacophores
Discovery of coumarin Mannich base derivatives as multifunctional agents against monoamine oxidase B and neuroinflammation for the treatment of Parkinson's disease
期刊论文
2019, 卷号: 173, 页码: 203-212
作者:
Tao, Deng
;
Wang, Yue
;
Bao, Xiu-Qi
;
Yang, Bei-Bei
;
Gao, Fan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Parkinson's disease
Multifunctional compounds
Coumarin Mannich base
MAO-B inhibitors
Anti-inflammatory effect
A coumarin-based dual optical probe for homocysteine with rapid response time, high sensitivity and selectivity
期刊论文
2019, 卷号: 196, 页码: 243-248
作者:
Wang, Kun-Peng
;
Xu, Shengnan
;
Lei, Yang
;
Zheng, Wen-Jun
;
Zhang, Qi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Sensor
Fluorescent probe
Dual optical probe
Homocysteine
Coumarin
Cell imaging
Synthesis and Biological Evaluation of Substituted Indole and Its Analogs as Influenza A Virus Inhibitors
期刊论文
2019, 卷号: 16, 期号: 2, 页码: e1800577
作者:
Zhang, Xuandi
;
Zhang, Guo-Ning
;
Wang, Yujia
;
Zhu, Mei
;
Wang, Juxian
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/01/03
influenza A virus
substitution and bioisosteric replacement
indole
naphthol
coumarin
cytotoxicity
antiviral activity
Coumarin glycosides from Hydrangea paniculata slow down the progression of diabetic nephropathy by targeting Nrf2 anti-oxidation and smad2/3-mediated profibrosis
期刊论文
2019, 卷号: 57, 页码: 385-395
作者:
Zhang, Sen
;
Wang, Weida
;
Ma, Jie
;
Sheng, Li
;
Zhang, Dongming
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Coumarin glycoside
Diabetic nephropathy
Hydrangea paniculata
Nrf2
Reactive oxygen species
Smad2/3
IMM-H004, a Novel Coumarin Derivative Compound, Inhibits H2O2 -Induced Neurotoxicity via Antioxidant and Antiapoptosis in PC12 Cells
期刊论文
2018, 卷号: 27, 期号: 12, 页码: 3396-3403
作者:
Song, Xiu-Yun
;
Hu, Jin-Feng
;
Wu, Dong-Hui
;
Ji, Hai-Jie
;
Chen, Nai-Hong
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/03
IMM H004
coumarin
hydrogen peroxide
oxidative stress
apoptosis
A new terpene coumarin microbial transformed by Mucor polymorphosporus induces apoptosis of human gastric cancer cell line MGC-803
期刊论文
2018, 卷号: 41, 期号: 6, 页码: 646-654
作者:
Li, Guangzhi
;
Wang, Junchi
;
Li, Xiaojin
;
Xu, Jianguo
;
Zhang, Zhao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Biotransformation
Mucor polymorphosporus
Terpene coumarin
Human gastric cancer MGC-803 cell line
Apoptosis
Bis-coumarin Derivatives and their Biological Activities
期刊论文
2018, 卷号: 18, 期号: 2, 页码: 101-113
作者:
Ren Qingcheng
;
Gao Chuan
;
Xu Zhi
;
Xu Yan
;
Liu Ming-Liang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Bis-coumarin
anti-bacterial
antitumor
antiviral
hybrid compounds
structure-activity relationships
Caspase-1 Specific Light-Up Probe with Aggregation-Induced Emission Characteristics for Inhibitor Screening of Coumarin-Originated Natural Products
期刊论文
2018, 卷号: 10, 期号: 15, 页码: 12173-12180
作者:
Lin, Hao
;
Yang, Haitao
;
Huan, Shuai
;
Wang, Fujia
;
Wang, Dong-Mei
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
aggregation-induced emission
light-up probe
caspase-1
coumarin
natural products
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