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科研机构
山东大学 [117]
内容类型
期刊论文 [114]
会议论文 [3]
发表日期
2019 [12]
2018 [6]
2017 [8]
2016 [11]
2015 [15]
2014 [14]
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专题:山东大学
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Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 2
作者:
Cui, Ying-Jie
;
Tang, Long-Qian
;
Zhang, Cheng-Mei
;
Liu, Zhao-Peng
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2019/12/11
privileged structure
pyrazoles
tubulin inhibitors
antitumor
antitumor agents
Yifei Tongluo, a Chinese Herbal Formula, Suppresses Tumor Growth and Metastasis and Exerts Immunomodulatory Effect in Lewis Lung Carcinoma Mice
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 4
作者:
Qi, Qiuchen
;
Hou, Yanhong
;
Li, Ang
;
Sun, Yueyue
;
Li, Siying
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/11
lung cancer
antitumor
anti-metastasis
apoptosis
MMPs
immunomodulatory
MAPK pathway
Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 73-86
作者:
Zhao, Wei
;
He, Long
;
Xiang, Tian-Le
;
Tang, Ya-Jie
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
Tubulin
Colchicine domain
Podophyllotoxin
Binding affinity
Nanomolar-potency antitumor activity
Recent Advance of Akt Inhibitors in Clinical Trials
期刊论文
CHEMISTRYSELECT, 2019, 卷号: 4, 期号: 31, 页码: 9040-9044
作者:
Guo, Kaiwen
;
Tang, Wendi
;
Zhuo, Huijun
;
Zhao, Guisen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
antitumor agents
clinical trials
inhibitors
protein kinase B
Modification, Antitumor Activity, and Targeted PPAR gamma Study of 18 beta-Glycyrrhetinic Acid, an Important Active Ingredient of Licorice
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 34, 页码: 9643-9651
作者:
Sun, Juan
;
Liu, Han-Yu
;
Lv, Cheng-Zhi
;
Qin, Jie
;
Wu, Yuan-Feng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
glycyrrhetic acid
molecular docking
piperazine
antitumor
PPAR gamma
Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain
期刊论文
European Journal of Medicinal Chemistry, 2019, 页码: 73-86
作者:
Zhao W.
;
He L.
;
Xiang T.-L.
;
Tang Y.-J.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Binding affinity
Colchicine domain
Nanomolar-potency antitumor activity
Podophyllotoxin
Tubulin
The inhibitory effect of polysaccharide from Rhizopus nigricans on colitis-associated colorectal cancer
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 112
作者:
Song, Ge
;
Lu, Yan
;
Yu, Zhidan
;
Xu, Lei
;
Liu, Jing
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
Polysaccharide
Colitis
Colitis-associated cancer
Mouse model
Antitumor effect
Purification of an acidic polysaccharide from Suaeda salsa plant and its anti-tumor activity by activating mitochondrial pathway in MCF-7 cells
期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 215, 页码: 99-107
作者:
Liu, Xinxin
;
Liu, Fei
;
Zhao, Shuo
;
Guo, Bin
;
Ling, Peixue
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
Suaeda salsa
Polysaccharide
Extraction
Antitumor activity
Design, synthesis, and biological evaluation of novel nitrogen heterocycle-containing ursolic acid analogs as antitumor agents
期刊论文
Molecules, 2019
作者:
Wang W.
;
Lei L.
;
Liu Z.
;
Wang H.
;
Meng Q.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
Antitumor activity
Apoptosis
Nitrogen heterocycles
Synthesis
Ursolic acid analogues
Design, Synthesis and Biological Evaluation of Novel Osimertinib-Based HDAC and EGFR Dual Inhibitors
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 13
作者:
Dong, Hang
;
Yin, Hao
;
Zhao, Chunlong
;
Cao, Jiangying
;
Xu, Wenfang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/11
HDAC
EGFR
multi-target inhibitor
antitumor
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