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科研机构
生物物理研究所 [5]
昆明植物研究所 [2]
上海药物研究所 [1]
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期刊论文 [8]
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学科主题:Biochemistry & Molecular Biology
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Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 14, 页码: 4218-4224
作者:
Zhu, Jinmei
;
Wu, Chun-Feng
;
Li, Xiaobing
;
Wu, Gui-Sheng
;
Xie, Shan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2013/10/16
Alzheimer's Disease
Acetylcholinesterase
Butyrylcholinesterase
Molecular Modeling
2-aminobenzimidazole
Metal Metabolic Homeostasis Disruption and Early Initiation of Mechanism for Alzheimer's Disease
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2012, 卷号: 39, 期号: 8, 页码: 756-763
Zhao Baolu
;
赵保路
;
Wan Li
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  |  
浏览/下载:12/0
  |  
提交时间:2013/12/24
Alzheimer's disease (AD)
metal iron homeostasis disruption
oxidative stress
beta-amyloid (A beta)
amyloid precursor protein (APP)
iron regulatory protein (IRP)
divalent metal transporter 1 (DMT1)
natural antioxidants
Endogenous and Exogenous Factors in Hyperphosphorylation of Tau in Alzheimer's Disease
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2012, 卷号: 39, 期号: 8, 页码: 778-784
Wei Yan
;
Miao JunYe
;
Liu Ying
;
刘缨
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  |  
浏览/下载:16/0
  |  
提交时间:2013/12/24
endogenous and exogenous factors
Alzheimer's disease
Tau protein
abnormal phosphorylation
Predicting memapsin 2 (beta-secretase) hydrolytic activity
期刊论文
PROTEIN SCIENCE, 2010, 卷号: 19, 期号: 11, 页码: 2175-2185
Li, Xiaoman
;
Bo, Huang
;
Zhang, Xuejun C
;
Hartsuck, Jean A
;
Tang, Jordan
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  |  
浏览/下载:17/0
  |  
提交时间:2013/12/24
memapsin 2
BACE1
beta-secretase
subsite specificity
activity prediction
beta-amyloid
Alzheimer's disease
Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 卷号: 17, 期号: 19, 页码: 6937-6941
作者:
Yan, Jian
;
Sun, Lirong
;
Wu, Guisheng
;
Yi, Ping
;
Yang, Fumei
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  |  
浏览/下载:14/0
  |  
提交时间:2012/03/21
Alzheimer's Disease
Hupzine a
Ache
Docking Study
Natural Antioxidants Protect Neurons in Alzheimer's Disease and Parkinson's Disease
期刊论文
NEUROCHEMICAL RESEARCH, 2009, 卷号: 34, 期号: 4, 页码: 630-638
Zhao, Baolu
;
赵保路
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  |  
浏览/下载:24/0
  |  
提交时间:2013/12/25
Oxidative stress
Green tea polyphenols
Nicotine
Genistein
Neurodegenerative diseases
Alzheimer's disease (AD)
Parkinson's disease (PD)
Divalent metal transporter 1 is involved in amyloid precursor protein processing and A beta generation
期刊论文
FASEB JOURNAL, 2009, 卷号: 23, 期号: 12, 页码: 4207-4217
Zheng, Wei
;
Xin, Na
;
Chi, ZhiHong
;
Zhao, BoLu
;
Zhang, Jie
;
Li, JiaYi
;
Wang, ZhanYou
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  |  
浏览/下载:13/0
  |  
提交时间:2013/12/25
beta-amyloid peptide
RNA interference
APP/PS1 transgenic mouse
Alzheimer's disease
divalent cation transporter 1
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