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科研机构
华中师范大学 [3]
大连理工大学 [2]
上海药物研究所 [2]
西安交通大学 [1]
上海应用物理研究所 [1]
山东大学 [1]
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期刊论文 [11]
发表日期
2019 [11]
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Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2019, 卷号: 1863, 期号: 7, 页码: 1167-1176
作者:
Lyu, Qianqian
;
Zhang, Keke
;
Shi, Yanhong
;
Li, Weihua
;
Diao, Xiaotong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Alginate lyase
PL-6
Catalytic mechanism
X-ray crystallography
Product distribution
Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 3, 页码: 953-967
作者:
Yan, Yan
;
Zhou, X. Edward
;
Novick, Scott J.
;
Shaw, Simon J.
;
Li, Yingwu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
AMP-activated kinase (AMPK)
AMP
hydrogen exchange mass spectrometry
X-ray crystallography
phosphorylation
activation loop phosphorylation
ADaM site
CBS3
R734
R739
metabolic disorder
energy sensor
Structural basis for activity of TRIC counter-ion channels in calcium release
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 页码: 4238-4243
作者:
Wang, Xiao-hui
;
Su, Min
;
Gao, Feng
;
Xie, Wenjun
;
Zeng, Yang
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/11/19
lipid modulation
electrophysiology
X-ray crystallography
Ca2+ modulation
counter-ion mechanism
Proton mediated spin state transition of cobalt heme analogs
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 2303
作者:
Zhao, Jianping
;
Peng, Qian
;
Wang, Zijian
;
Xu, Wei
;
Xiao, Hongyan
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/12/02
cobalt
cytochrome P450
heme
histidine
imidazole
imidazole derivative
iron
ligand
proton, analogs and derivatives
biocatalysis
chemistry
electron spin resonance
metabolism
oxidation reduction reaction
pH
X ray crystallography, Biocatalysis
Cobalt
Crystallography, X-Ray
Cytochrome P-450 Enzyme System
Electron Spin Resonance Spectroscopy
Heme
Histidine
Hydrogen-Ion Concentration
Imidazoles
Iron
Ligands
Oxidation-Reduction
Protons
Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 页码: 9358-9364
作者:
Chen, Wei
;
Zhou, Yong
;
Yang, Qing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/02
glycoside hydrolase
inhibitor
inhibition mechanism
insect
protein crystallization
Asian corn borer (Ostrinia furnacalis)
ecdysis
group II chitinase
inhibitor design
X-ray crystallography
Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
期刊论文
The Journal of biological chemistry, 2019
作者:
Pengfei Wang
;
Yanan Zuo
;
Jianfeng Sun
;
Teng Zuo
;
Senyan Zhang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/17
H5N1
HPAI
X-ray
crystallography
epitope
infectious
disease
influenza
influenza
virus
monoclonal
antibody
mutagenesis
neutralizing
antibody
structural
biology
vaccine
development
virology
vulnerable
site
Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2019, 卷号: 1863, 期号: 7, 页码: 1167-1176
作者:
Lyu, Qianqian
;
Zhang, Keke
;
Shi, Yanhong
;
Li, Weihua
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
Alginate lyase
PL-6
Catalytic mechanism
X-ray crystallography
Product distribution
Halogen bonding and host-guest chemistry between N-alkylammonium resorcinarene halides, diiodoperfluorobutane and neutral guests.
期刊论文
Beilstein journal of organic chemistry, 2019, 卷号: 15, 页码: 947-954
作者:
Pan, Fangfang*
;
Dashti, Mohadeseh
;
Reynolds, Michael R.
;
Rissanen, Kari
;
Trant, John F.*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
X-ray crystallography
capsule
dimeric assemblies
halogen bonding
host-guest chemistry
resorcinarene salts
Pyrazole-Isoindoline-1,3-dione Hybrid: A Promising Scaffold for 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 39, 页码: 10844-10852
作者:
He, Bo
;
Dong, Jin
;
Lin, Hong-Yan
;
Wang, Meng-Yao
;
Li, Xian-Kai
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/23
4-hydroxyphenylpyruvate dioxygenase
X-ray crystallography
inhibition kinetics
isoindoline-1,3-dione
pyrazole
Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations
期刊论文
The FEBS journal, 2019, 卷号: 286, 期号: 5, 页码: 975-990
作者:
Lin, Hong-Yan
;
Yang, Jing-Fang
;
Wang, Da-Wei
;
Hao, Ge-Fei
;
Dong, Jiang-Qing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/23
4-hydroxyphenylpyruvate dioxygenase
X-ray crystallography
computational simulations
herbicide
inhibition kinetics
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