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四川大学 [5]
上海药物研究所 [3]
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山东大学 [3]
复旦大学上海医学院 [3]
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期刊论文 [37]
发表日期
2018 [37]
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From hit to lead: Structure-based discovery of naphthalene-1 sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 44-59
作者:
Gao, Ding-Ding
;
Dou, Hui-Xia
;
Su, Hai-Xia
;
Zhang, Ming-Ming
;
Wang, Ting
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
FABP4 inhibitors
FABP3 sparing
Structure-based design strategy
X-ray crystallography
Druggable negative allosteric site of P2X3 receptors
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 19, 页码: 4939-4944
作者:
Wang, Jin
;
Wang, Yao
;
Cui, Wen-Wen
;
Huang, Yichen
;
Yang, Yang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
P2X3 receptors
allosteric inhibition
X-ray crystallography
AF-219
AF-353
Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion
期刊论文
FASEB JOURNAL, 2018, 卷号: 32, 期号: 5, 页码: 2411-2421
作者:
Xin, Yanlong
;
Zhao, Yan
;
Zheng, Jiangge
;
Zhou, Haizhen
;
Zhang, Xuejun Cai
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/08/23
X-ray crystallography
YidC/Oxa1/Alb3
membrane protein insertase
membrane protein biogenesis
Structural Characterization and Optimization of Extraction of Microcrystalline Cellulose from Jerusalem artichoke Stalk
期刊论文
Journal of Chinese Institute of Food Science and Technology, 2018, 卷号: 18, 期号: 1, 页码: 119-127
作者:
Ren, Haiwei
;
Shen, Jiali
;
Zhu, Xiaoqian
;
Zhang, Bingyun
;
Fan, Wenguang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2022/02/17
Extraction
Fourier transform infrared spectroscopy
Hydrochloric acid
Microcrystals
Polymerization
Structural optimization
Surface properties
X ray crystallography
Degree of polymerization
FT-IR investigation
Jerusalem artichoke
Micro-crystalline cellulose
Polymerization degree
Response surface methodology
Single-factor experiments
Structural characterization
Structural Characterization and Optimization of Extraction of Microcrystalline Cellulose from Jerusalem artichoke Stalk
期刊论文
Journal of Chinese Institute of Food Science and Technology, 2018, 卷号: 18, 期号: 1, 页码: 119-127
作者:
Ren, Haiwei
;
Shen, Jiali
;
Zhu, Xiaoqian
;
Zhang, Bingyun
;
Fan, Wenguang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/11/14
Crystalline materials
Extraction
Fourier transform infrared spectroscopy
Hydrochloric acid
Polymerization
Structural optimization
Surface properties
X ray crystallography
Degree of polymerization
FT-IR investigation
Jerusalem artichoke
Micro-crystalline cellulose
Polymerization degree
Response surface methodology
Single-factor experiments
Structural characterization
Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (pdilt) provide insight into its chaperone activity
期刊论文
Journal of biological chemistry, 2018, 卷号: 293, 期号: 4, 页码: 1192-1202
作者:
Li, Huanhuan
;
Yang, Kai
;
Wang, Wenjia
;
Niu, Yingbo
;
Li, Jun
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  |  
浏览/下载:51/0
  |  
提交时间:2019/04/23
Conformational change
Molecular chaperone
Protein structure
Small-angle x-ray scattering (saxs)
X-ray crystallography
From hit to lead: Structure-based discovery of naphthalene-1 sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154
作者:
Gao, Ding-Ding
;
Dou, Hui-Xia
;
Su, Hai-Xia
;
Zhang, Ming-Ming
;
Wang, Ting
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
FABP4 inhibitors
FABP3 sparing
Structure-based design strategy
X-ray crystallography
Formation of Cys-heme cross-link in K42C myoglobin under reductive conditions with molecular oxygen
期刊论文
JOURNAL OF INORGANIC BIOCHEMISTRY, 2018, 卷号: 182
作者:
Cheng, Hui-Min
;
Yuan, Hong
;
Wang, Xiao-Juan
;
Xu, Jia-Kun
;
Gao, Shu-Qin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Heme proteins
Protein design
Cross-link
Mechanism
X-ray crystallography
Druggable negative allosteric site of P2X3 receptors
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 19
作者:
Wang, Jin
;
Wang, Yao
;
Cui, Wen-Wen
;
Huang, Yichen
;
Yang, Yang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
P2X3 receptors
allosteric inhibition
X-ray crystallography
AF-219
AF-353
Structure-based discovery of selective BRPF1 bromodomain inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 155
作者:
Zhu, Jian
;
Zhou, Chunxian
;
Caflisch, Amedeo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
BRPF1 bromodomain
Pharmacophore search
Structure-based drug design
X-ray crystallography
Isothermal titration calorimetry
Molecular dynamics
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