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浏览/检索结果: 共4条，第1-4条 帮助 限定条件 发表日期：2014     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 小分子抑制剂与Mcl-1蛋白作用模式及分子优化的研究 学位论文 : 大连理工大学, 2014 作者:  陈清斌 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 ~1H-~(15)N HSQC二维核磁  小分子抑制剂  Mcl-1  结合模式  分子对接   高效液相色谱与核磁共振波谱在复杂生物混合物体系代谢物鉴定中的应用 会议论文 第十八届全国波谱学学术年会, 杭州, 2014-10-10 作者:  苗朝霞;  刘洪月;  郭维;  王映红 收藏  |  浏览/下载：1/0  |  提交时间：2020/01/13 代谢物  代谢产物  HSQC  Figure   Activity-guided isolation of NF-κB inhibitors and PPARγ agonists from the root bark of Lycium chinense Miller 期刊论文 Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 3, 页码: 470-477 作者:  Xie, Lian-Wu;  Atanasov, Atanas G.;  Guo, De-An;  Malainer, Clemens;  Zhang, Jing-Xian 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/28 1D NMR  one-dimensional nuclear magnetic resonance spectroscopy  2D NMR  two-dimensional nuclear magnetic resonance spectroscopy  ANOVA  analysis of variance  AP-1  activator protein 1  CC  column chromatography  CDCl3  deuterated chloroform  C/EBP  CCAAT/enhancer binding protein  CHCl3  chloroform  COSY  correlation spectroscopy in 2D NMR  DCM  dichloromethane  EGFP  enhanced green fluorescent protein  ESI-MS  electrospray ionization mass spectrometry  DMEM  Dulbecco׳s modified Eagle׳s medium  DMSO  dimethyl sulfoxide  EtOAc  ethyl acetate  EtOH  ethanol  FBS  fetal bovine serum  HEK293  human embryonic kidney 293  HMBC  heteronuclear multiple-bond correlation spectroscopy in 2D NMR  HPLC  high performance liquid chromatography  HSQC  heteronuclear single-quantum correlation spectroscopy in 2D NMR  IC50  half maximal inhibitory concentration  IκB  inhibitor of kappa B  IL-6  interleukin 6  IL-1β  interleukin-1 beta  MeOH  methanol  NF-κB  nuclear factor κB  NMR  nuclear magnetic resonance spectroscopy  PE  petroleum ether  PPARγ  peroxisome proliferator-activated receptor γ  TCM  traditional Chinese medicine  TLC  thin layer chromatography  TNF-α  tumor necrosis factor α  Trans-N-(p-coumaroyl)tyramine (PubChem CID: 5372945)  Trans-N-feruloyltyramine (PubChem CID: 5280537)  Trans-N-caffeoyltyramine (PubChem CID: 9994897)  Dihydro-N-caffeoyltyramine (PubChem CID: 16119668)  CHEMBL2337120 (PubChem CID: 71524307)  CHEMBL2337119 (PubChem CID: 71524308)  CHEMBL2337118 (PubChem CID: 71524309)  CHEMBL2337115 (PubChem CID: 71719510)  CHEMBL2337117 (PubChem CID: 71524310)  Lycium chinense Miller  Lycii Radicis Cortex  NF-κB  PPARγ  Phenolic amides  Fatty acids   Activity-guided isolation of NF-κB inhibitors and PPARγ agonists from the root bark of Lycium chinense Miller 期刊论文 Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 3, 页码: 470-477 作者:  Xie, Lian-Wu;  Atanasov, Atanas G.;  Guo, De-An;  Malainer, Clemens;  Zhang, Jing-Xian 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/27 1D NMR  one-dimensional nuclear magnetic resonance spectroscopy  2D NMR  two-dimensional nuclear magnetic resonance spectroscopy  ANOVA  analysis of variance  AP-1  activator protein 1  CC  column chromatography  CDCl3  deuterated chloroform  C/EBP  CCAAT/enhancer binding protein  CHCl3  chloroform  COSY  correlation spectroscopy in 2D NMR  DCM  dichloromethane  EGFP  enhanced green fluorescent protein  ESI-MS  electrospray ionization mass spectrometry  DMEM  Dulbecco׳s modified Eagle׳s medium  DMSO  dimethyl sulfoxide  EtOAc  ethyl acetate  EtOH  ethanol  FBS  fetal bovine serum  HEK293  human embryonic kidney 293  HMBC  heteronuclear multiple-bond correlation spectroscopy in 2D NMR  HPLC  high performance liquid chromatography  HSQC  heteronuclear single-quantum correlation spectroscopy in 2D NMR  IC50  half maximal inhibitory concentration  IκB  inhibitor of kappa B  IL-6  interleukin 6  IL-1β  interleukin-1 beta  MeOH  methanol  NF-κB  nuclear factor κB  NMR  nuclear magnetic resonance spectroscopy  PE  petroleum ether  PPARγ  peroxisome proliferator-activated receptor γ  TCM  traditional Chinese medicine  TLC  thin layer chromatography  TNF-α  tumor necrosis factor α  Trans-N-(p-coumaroyl)tyramine (PubChem CID: 5372945)  Trans-N-feruloyltyramine (PubChem CID: 5280537)  Trans-N-caffeoyltyramine (PubChem CID: 9994897)  Dihydro-N-caffeoyltyramine (PubChem CID: 16119668)  CHEMBL2337120 (PubChem CID: 71524307)  CHEMBL2337119 (PubChem CID: 71524308)  CHEMBL2337118 (PubChem CID: 71524309)  CHEMBL2337115 (PubChem CID: 71719510)  CHEMBL2337117 (PubChem CID: 71524310)  Lycium chinense Miller  Lycii Radicis Cortex  NF-κB  PPARγ  Phenolic amides  Fatty acids