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科研机构
生态环境研究中心 [13]
内容类型
期刊论文 [13]
发表日期
2020 [3]
2019 [3]
2017 [3]
2016 [2]
2011 [2]
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Potent Oxidation of DNA by Haloquinoid Disinfection Byproducts to the More Mutagenic Imidazolone dlz via an Unprecedented Haloquinone-Enoxy Radical-Mediated Mechanism
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 10, 页码: 6244-6253
作者:
Shao, Jie
;
Huang, Chun-Hua
;
Shao, Bo
;
Qin, Li
;
Xu, Dan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/09/14
An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 150-159
作者:
Zhu, Ben-Zhan
;
Xu, Dan
;
Qin, Li
;
Huang, Chun-Hua
;
Xie, Lin-Na
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/09/14
N-centered amidyl radical
Nitroxide radical
Hydrogen-abstraction
Tetrachloroquinoid compounds
N-alkyl hydroxamic acids
Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 70-78
作者:
Huang, Chun-Hua
;
Xu, Dan
;
Qin, Li
;
Tang, Tian-Shu
;
Shan, Guo-Qiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/09/14
N-alkyl hydroxamic acids
N-centered radicals
Chlorinated quinones
Carbon-nitrogen bonding conjugate
DNA adducts
Molecular mechanism for the activation of the anti-tuberculosis drug isoniazid by Mn(III): First detection and unequivocal identification of the critical N-centered isoniazidyl radical and its exact location
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 143, 页码: 232-239
作者:
Qin, Li
;
Huang, Chun-Hua
;
Xu, Dan
;
Xie, Lin-Na
;
Shao, Jie
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/09/10
Isoniazid
Mn(III)(Acetate) 3
Isoniazidyl radical
Distal-nitrogen of the hydrazine group
Diisonicotinyl hydrazine
Mechanism of unprecedented hydroxyl radical production and site-specific oxidative DNA damage by photoactivation of the classic arylhydroxamic acid carcinogens
期刊论文
CARCINOGENESIS, 2019, 卷号: 40, 期号: 9, 页码: 1153-1163
作者:
Xu, Dan
;
Huang, Chun-Hua
;
Xie, Lin-Na
;
Shao, Bo
;
Mao, Li
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/09/10
An unusual double radical homolysis mechanism for the unexpected activation of the aldoxime nerve-agent antidotes by polyhalogenated quinoid carcinogens under normal physiological conditions
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 130, 页码: 1-7
作者:
Xie, Lin-Na
;
Shao, Jie
;
Huang, Chun-Hua
;
Li, Feng
;
Xu, Dan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/10/21
Radical homolysis mechanism
Iminyl radical
Tetrachloro-1, 4-benzoquinone (TCBQ)
Pyridinium aldoximes
Nerve-agent antidotes
Polyhalogenated quinoid carcinogens
Mechanism of Intrinsic Chemiluminescence Production from the Degradation of Persistent Chlorinated Phenols by the Fenton System: A Structure-Activity Relationship Study and the Critical Role of Quinoid and Semiquinone Radical Intermediates
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 卷号: 51, 期号: 5, 页码: 2934-2943
作者:
Gao, Hui-Ying
;
Mao, Li
;
Li, Feng
;
Xie, Lin-Na
;
Huang, Chun-Hua
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2018/07/26
Mechanism of synergistic DNA damage induced by the hydroquinone metabolite of brominated phenolic environmental pollutants and Cu(II): Formation of DNA-Cu complex and site-specific production of hydroxyl radicals
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2017, 卷号: 104, 期号: 0, 页码: 54-63
作者:
Mao, Li
;
Shao, Bo
;
Qu, Na
;
Wang, Ya-Fen
;
Gao, Hui-Ying
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2018/07/26
Cu(Ii)
2
6-dibromohydroquinone
Site-specific Mechanism
Dna Strand Breakage 8-oxo-7
Hydroxyl Radical
8-dihydro-2 '-deoxyguanosine Formation
Unusual Double Beckmann Fragmentation Reaction under Physiological Conditions
期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 82, 期号: 24, 页码: 13084-13092
作者:
Kalyanaraman, Balaraman
;
Xie, Lin-Na
;
Huang, Chun-Hua
;
Xu, Dan
;
Li, Feng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2018/07/26
An Exceptionally Facile Two-Step Structural Isomerization and Detoxication via a Water-Assisted Double Lossen Rearrangement
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 0
作者:
Li, Feng
;
Huang, Chun-Hua
;
Xie, Lin-Na
;
Qu, Na
;
Shao, Jie
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2017/03/27
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