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中国医学科学院 北... [42]
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期刊论文 [42]
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2019 [11]
2018 [12]
2017 [8]
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专题:中国医学科学院 北京协和医学院
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hERG optimizations of IMB1603, discovery of alternative benzothiazinones as new antitubercular agents
期刊论文
2019, 卷号: 179, 页码: 208-217
作者:
Lv Kai
;
Wang Apeng
;
Tao Zeyu
;
Fu Lei
;
Liu Hongtao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
Antitubercular agents
Benzothiazinones
Structure-activity relationships
hERG
Targeting Extracellular Heat Shock Protein 70 Ameliorates Doxorubicin-Induced Heart Failure Through Resolution of Toll-Like Receptor 2-Mediated Myocardial Inflammation
期刊论文
2019, 卷号: 8, 期号: 20, 页码: e012338
作者:
Liu Peng
;
Bao Hua-Yan
;
Jin Cai-Cai
;
Zhou Ji-Chao
;
Hua Fang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
cardiac dysfunction
cardiac remodeling
damage‐associated molecular patterns
nuclear factor‐κB
toll‐like receptor
Identification of benzothiazinones containing an oxime functional moiety as new anti-tuberculosis agents
期刊论文
2019, 卷号: 181, 页码: 111595
作者:
Wang Apeng
;
Lv Kai
;
Tao Zeyu
;
Gu Jian
;
Fu Lei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Antimycobacterial activity
Benzothiazinones
Oximes
Synthesis
Design, synthesis and biological activity of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides as new antitubercular agents
期刊论文
2019, 卷号: 178, 页码: 715-725
作者:
Wang, Apeng
;
Lv, Kai
;
Li, Linhu
;
Liu, Hongtao
;
Tao, Zeyu
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/01/03
imidazo[1
2-a]pyridine
Design
Synthesis
Antimycobacterial activity
Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring autophagy and suppressing exosome-mediated HSC activation
期刊论文
2019, 页码: 1-15
作者:
Zhang Xiao-Wei
;
Zhou Ji-Chao
;
Peng Dian
;
Hua Fang
;
Li Ke
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/01/03
Exosome
helical peptide
liver injury
protein-protein interaction
tribbles pseudokinase
Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages
期刊论文
2019, 卷号: 51, 期号: 3, 页码: 522-534.e7
作者:
Liu Shan-Shan
;
Lv Xiao-Xi
;
Liu Chang
;
Qi Jie
;
Li Yun-Xuan
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/01/03
E3 ligase
UPS
inflammation
lung injury
protein-protein interaction
pulmonary fibrosis
ubiquitination
α-helical peptide
Outcomes of different rehabilitative procedures in patients with pulmonary atresia, ventricular septal defect and major aortopulmonary collateral arteries
期刊论文
2019, 卷号: 55, 期号: 5, 页码: 837-844
作者:
Zhao Dong
;
Yang Keming
;
Li Shoujun
;
Yan Jun
;
Hua Zhongdong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/01/03
Central shunt
Major aortopulmonary collateral artery
Pulmonary atresia
Rehabilitation
Right ventricle to pulmonary artery connection
TRIB3 Interacts With beta-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis
期刊论文
2019, 卷号: 156, 期号: 3, 页码: 708-+
作者:
Hua, Fang
;
Shang, Shuang
;
Yang, Yu-wei
;
Zhang, Hai-zeng
;
Xu, Tian-lei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/01/03
Colon Cancer
Carcinogenesis
Mouse Model
Tumor Development
Chronic stress: a crucial promoter of cell apoptosis in atherosclerosis
期刊论文
2019, 页码: 300060518814606
作者:
Meng Ling-Bing
;
Shan Meng-Jie
;
Yu Ze-Mou
;
Lv Jian
;
Qi Ruo-Mei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Chronic stress
atherosclerosis
balloon injury
cell apoptosis
high-fat diet
proteomics
rabbit model
Highlights of the 2nd International Symposium on Tribbles and Diseases: tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer
期刊论文
2019, 卷号: 9, 期号: 2, 页码: 443-454
作者:
Cui, Bing
;
Eyers, Patrick A.
;
Dobens, Leonard L.
;
Tan, Nguan Soon
;
Mace, Peter D.
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/01/03
Tribbles
Immunology
Metabolism
Cell biology
Kinase inhibitor
Tumorigenesis
Metastasis
TRIB1
TRIB2
TRIB3
Pseudokinase
Inflammation
Atomic structure
Protein quality control
Ubiqutin
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