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中国医学科学院 北... [11]
内容类型
期刊论文 [11]
发表日期
2019 [2]
2017 [4]
2016 [3]
2015 [1]
2014 [1]
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专题:中国医学科学院 北京协和医学院
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Polygala tenuifolia-Acori tatarinowii herbal pair as an inspiration for substituted cinnamic α-asaronol esters: Design, synthesis, anticonvulsant activity, and inhibition of lactate dehydrogenase study
期刊论文
2019, 卷号: 183, 页码: 111650
作者:
Bai Yajun
;
He Xirui
;
Bai Yujun
;
Sun Ying
;
Zhao Zefeng
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/01/03
Anticonvulsant compounds
Combination of traditional Chinese medicine molecular chemistry
Lactate dehydrogenase inhibitor
Polygala tenuifolia-Acori tatarinowii herbal pair
LC-MS/MS-based quantification of tryptophan metabolites and neurotransmitters in the serum and brain of mice
期刊论文
2019, 卷号: 1112, 页码: 24-32
作者:
Wang, Li-Sha
;
Zhang, Meng-Di
;
Tao, Xue
;
Zhou, Yun-Feng
;
Liu, Xin-Min
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
Liquid chromatography-tandem mass
spectrometry
Tryptophan
Kynurenine
Metabolite
Neurotransmitter
Depression
Loss of LKB1 Expression Decreases the Survival and Promotes Laryngeal Cancer Metastasis
期刊论文
2017, 卷号: 8, 期号: 17, 页码: 3548-3554
作者:
He, Sha-sha
;
Chen, Yong
;
Wang, Hong-zhi
;
Shen, Xiao-ming
;
Sun, Peng
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/03
Laryngeal squamous cell carcinoma
liver kinase B1 (LKB1)
p16INK4a (p16)
prognosis
A rapid and efficient analytical method for the quantification of a novel anticholinergic compound, R-phencynonate, by stable isotope-dilution LC-MS/MS and its application to bioavailability and dose proportionality studies
期刊论文
2017, 卷号: 31, 期号: 5
作者:
Li Jinglai
;
Liao Sha
;
Wang Xiaoying
;
Liu Qian
;
Meng Fei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/04
bioavailability
dose proportionality
pharmacokinetics
R-phencynonate
stable isotope-dilution LC-MS/MS
Plasma and brain pharmacokinetics of ganoderic acid A in rats determined by a developed UFLC-MS/MS method
期刊论文
2017, 卷号: 1052, 页码: 19-26
作者:
Cao Fang-Rui
;
Xiao Bing-Xin
;
Wang Li-Sha
;
Tao Xue
;
Yan Ming-Zhu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
Ganoderic acid A
UFLC-MS/MS
Pharmacokinetics
Plasma
Brain microdialysis
Pharmacokinetics of Cajaninstilbene Acid and Its Main Glucuronide Metabolite in Rats
期刊论文
2017, 卷号: 65, 期号: 20, 页码: 4066-4073
作者:
Wang Li-Sha
;
Tao Xue
;
Pan Rui-Le
;
Cao Fang-Rui
;
Feng Li
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
cajaninstilbene acid
pharmacokinetics
bioavailability
glucuronide metabolite
Anti-stress effects of ginseng total saponins on hindlimb-unloaded rats assessed by a metabolomics study
期刊论文
2016, 卷号: 188, 页码: 39-47
作者:
Feng, Li
;
Liu, Xin-min
;
Cao, Fang-rui
;
Wang, Li-sha
;
Chen, Yi-xi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Ginseng total saponins
Hindlimb unloading
Stress
LC/MS
Urine
Metabolomics
LC/MS-based metabolomics strategy to assess the amelioration effects of ginseng total saponins on memory deficiency induced by simulated microgravity
期刊论文
2016, 卷号: 125, 页码: 329-338
作者:
Feng, Li
;
Yue, Xiao-fei
;
Chen, Yi-xi
;
Liu, Xin-min
;
Wang, Li-sha
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/04
Metabolomics
Plasma
Hippocampus
Ginseng total saponins
Memory-improving effects
LC/MS
Lotus leaf alkaloid fraction can strongly inhibit CYP2D6 isoenzyme activity
期刊论文
2016, 卷号: 194, 页码: 913-917
作者:
Ye, Lin-Hu
;
Kong, Ling-Ti
;
Yan, Ming-Zhu
;
Cao, Fang-Rui
;
Wang, Li-Sha
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
Lotus
Nelumbo nucifera
Alkaloid
CYP2D6
Drug interaction
Organ-Specific Microenvironment Modifies Diverse Functional and Phenotypic Characteristics of Leukemia-Associated Macrophages in Mouse T Cell Acute Lymphoblastic Leukemia
期刊论文
2015, 卷号: 194, 期号: 6, 页码: 2919-2929
作者:
Chen, Sha-Yan
;
Yang, Xiao
;
Feng, Wen-Li
;
Liao, Jin-Feng
;
Wang, Li-Na
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/01/13
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