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IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文
2019, 卷号: 212, 页码: 36-53
作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun
收藏  |  浏览/下载:26/0  |  提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator  
IMM-H004 Protects against Cerebral Ischemia Injury and Cardiopulmonary Complications via CKLF1 Mediated Inflammation Pathway in Adult and Aged Rats 期刊论文
2019, 卷号: 20, 期号: 7
作者:  Ai, Qidi;  Chen, Chen;  Chu, Shifeng;  Luo, Yun;  Zhang, Zhao
收藏  |  浏览/下载:7/0  |  提交时间:2020/01/03
A20 as a novel target for the anti-neuroinflammatory effect of chrysin via inhibition of NF-kappa B signaling pathway 期刊论文
2019, 卷号: 79, 页码: 228-235
作者:  Li, Zhipeng;  Chu, Shifeng;  He, Wenbin;  Zhang, Zhao;  Liu, Jiaqi
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/03
IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization 期刊论文
2019, 卷号: 70, 页码: 69-79
作者:  Chen, Chen;  Ai, Qidi;  Chu, Shifeng;  Zhang, Zhao;  Zhou, Xin
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/03
Hypouricemic and Nephroprotective Effects of an Active Fraction from Polyrhachis Vicina Roger On Potassium Oxonate-Induced Hyperuricemia in Rats 期刊论文
2018, 卷号: 43, 期号: 1, 页码: 220-233
作者:  Su, Qibiao;  Su, Hua;  Nong, Zhihuan;  Li, Dongmei;  Wang, Laiyou
收藏  |  浏览/下载:8/0  |  提交时间:2020/01/03
Early Stage Functions of Mitochondrial Autophagy and Oxidative Stress in Acetaminophen-Induced Liver Injury 期刊论文
2017, 卷号: 118, 期号: 10, 页码: 3130-3141
作者:  Gao Yan;  Chu Shifeng;  Zhang Zhao;  Zuo Wei;  Xia Congyuan
收藏  |  浏览/下载:1/0  |  提交时间:2020/01/04
Hepataprotective effects of ginsenoside Rg1-A review 期刊论文
2017, 卷号: 206, 页码: 178-183
作者:  Gao Yan;  Chu Shifeng;  Zhang Zhao;  Chen Naihong
收藏  |  浏览/下载:1/0  |  提交时间:2020/01/04
Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC-MS/MS: Rg1 excretion in rat bile, urine and feces 期刊论文
2016, 卷号: 6, 期号: 6, 页码: 593-599
作者:  He, Chiyu;  Feng, Ru;  Sun, Yupeng;  Chu, Shifeng;  Chen, Ji
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/04
Anti-inflammatory function of ginsenoside Rg1 on alcoholic hepatitis through glucocorticoid receptor related nuclear factor-kappa B pathway 期刊论文
2015, 卷号: 173, 页码: 231-240
作者:  Gao, Yan;  Chu, Shifeng;  Li, Jingwei;  Li, Jianping;  Zhang, Zhao
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/04
Tyrosine 402 Phosphorylation of Pyk2 Is Involved in Ionomycin-Induced Neurotransmitter Release 期刊论文
2014, 卷号: 9, 期号: 4, 页码: e94574
作者:  Zhang, Zhao;  Zhang, Yun;  Mou, Zheng;  Chu, Shifeng;  Chen, Xiaoyu
收藏  |  浏览/下载:11/0  |  提交时间:2020/01/13


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