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科研机构
山东大学 [11]
内容类型
期刊论文 [11]
发表日期
2019 [2]
2018 [4]
2017 [1]
2016 [3]
2014 [1]
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专题:山东大学
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Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 8, 页码: 3898-3923
作者:
Liang, Xuewu
;
Zang, Jie
;
Li, Xiaoyang
;
Tang, Shuai
;
Huang, Min
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/11
Novel-targeted therapy for hematological malignancies with JAK and HDAC dual inhibitors
期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1849-1852
作者:
Liang, Xuewu
;
Liu, Hong
;
Zhang, Yingjie
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
dual inhibitors
HDAC
hematological malignancies
JAK
multiple target
drugs
JAK/STAT Signal Transduction: Promising Attractive Targets for Immune, Inflammatory and Hematopoietic Diseases
期刊论文
CURRENT DRUG TARGETS, 2018, 卷号: 19, 期号: 5, 页码: 487-500
作者:
Gao, Qianwen
;
Liang, Xuewu
;
Shaikh, Abdul Sami
;
Zang, Jie
;
Xu, Wenfang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Inflammation
JAK
STAT
kinase inhibitors
selectivity
signal
transduction
Discovery of Novel Pazopanib-Based HDAC and VEGFR Dual Inhibitors Targeting Cancer Epigenetics and Angiogenesis Simultaneously
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 12, 页码: 5304-5322
作者:
Zang, Jie
;
Liang, Xuewu
;
Huang, Yongxue
;
Jia, Yuping
;
Li, Xiaoyang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3145-3157
作者:
Cao, Jiangying
;
Ma, Chunhua
;
Zang, Jie
;
Gao, Shuai
;
Gao, Qianwen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Aminopeptidase N
CD13
Anti-angiogenesis
Anti-metastasis
Triazole
Advances on graphene-based nanomaterials for biomedical applications
期刊论文
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2018, 卷号: 90, 页码: 764-780
作者:
Qu, Ying
;
He, Feng
;
Yu, Chenggong
;
Liang, Xuewu
;
Liang, Dong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Graphene
Physicochemical properties
Biocompatibility
Bio-imaging
Delivery
Phototherapy
Tissue engineering
Development of N-hydroxycinnamamide-based HDAC inhibitors with improved HDAC inhibitory activity and in vitro antitumor activity
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 9, 页码: 2666-2675
作者:
Zang, Jie
;
Shi, Baowen
;
Liang, Xuewu
;
Gao, Qianwen
;
Xu, Wenfang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
HDAC
Inhibitors
Antiproliferative activity
Selectivity
Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 108, 页码: 21-27
作者:
Ma, Chunhua
;
Cao, Jiangying
;
Liang, Xuewu
;
Huang, Yongxue
;
Wu, Ping
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/16
Aminopeptidase N
Inhibitors
Leucine ureido derivatives
Synthesis
Design, Synthesis, and Antitumor Evaluation of 4-Amino-(1H)-pyrazole Derivatives as JAKs Inhibitors
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 7, 期号: 10, 页码: 950-955
作者:
Liang, Xuewu
;
Zang, Jie
;
Zhu, Mengyuan
;
Gao, Qianwen
;
Wang, Binghe
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/16
JAKs
Inhibitors
4-Amino-(1H)-pyrazole
Anticancer
Design, synthesis and preliminary biological evaluation of 4-aminopyrazole derivatives as novel and potent JAKs inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2660-2672
作者:
Liang, Xuewu
;
Huang, Yongxue
;
Zang, Jie
;
Gao, Qianwen
;
Wang, Binghe
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/16
Inhibitors
JAKs
Kinase
4-Aminopyrazole
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