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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 专题：昆明植物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Two New 2(1H)-Pyrazinone Derivatives from the Plant Endophyte Streptomyces sp. KIB-H1992 期刊论文 RECORDS OF NATURAL PRODUCTS, 2020 作者:  Ma, Xiao-yan;  Zhang, Zhouxin;  Wang, Li;  Hu, Xinjun;  Liu, Xingyong 收藏  |  浏览/下载：12/0  |  提交时间：2021/01/05 Computational simulation studies on the binding selectivity of Wee1 and Checkpoint kinase 1 by molecular dynamics simulation combined with free energy calculations 期刊论文 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020 作者:  Li, Yaping;  Liu, Xingyong;  Zhang, Shuqun;  Wang, Liangliang;  Zhang, Li 收藏  |  浏览/下载：52/0  |  提交时间：2021/01/05 Design and synthesis of novel artemisinin hybrids with potent activities against human colorectal cancer cells in vitro and in vivo (vol 182, 111665, 2019) 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020 作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li 收藏  |  浏览/下载：8/0  |  提交时间：2021/01/05 Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文 BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13 作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li 收藏  |  浏览/下载：14/0  |  提交时间：2020/03/18 Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine   Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 10 作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li 收藏  |  浏览/下载：17/0  |  提交时间：2020/03/02 Artemisinin  Quinazoline  Hybridization  Colorectal cancer  Chemotherapy   Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176 作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping 收藏  |  浏览/下载：65/0  |  提交时间：2019/07/29 Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator   Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316 作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping 收藏  |  浏览/下载：57/0  |  提交时间：2019/03/25 IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS   Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60 作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying 收藏  |  浏览/下载：29/0  |  提交时间：2018/11/12 Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations   Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation 期刊论文 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915 作者:  Li, Yaping;  Pu, Yinglan;  Liu, Hui;  Zhang, Li;  Liu, Xingyong 收藏  |  浏览/下载：50/0  |  提交时间：2018/11/06 Wee1 inhibitors  Pharmacophore model  Molecular docking  Virtual screening  Molecular dynamics simulation   Pharmacophore modeling, molecular docking and molecular dynamics studies on natural products database to discover novel skeleton as non-puricie xanthine oxidase inhibitors 期刊论文 PLASTID GENOME EVOLUTION, 2018, 卷号: 85, 页码: 293-313 作者:  Peng, Jiale;  Li, Yaping;  Zhou, Yeheng;  Zhang, Li;  Liu, Xingyong 收藏  |  浏览/下载：24/0  |  提交时间：2018/12/27