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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Preclinical characterization of LOXO-338, a novel, oral and selective BCL2 inhibitor. 期刊论文 CANCER RESEARCH, 2021, 卷号: 81, 期号: 13, 页码: 1 作者:  Brandhuber, Barbara;  Ku, Karin;  Lallena, Maria J.;  Baquero, Carmen;  Choy, Regina 收藏  |  浏览/下载：12/0  |  提交时间：2021/11/04 Quantitative proteomics reveals Shexiang Baoxin Pill exerts cardioprotective effects by preserving energy metabolism in a rat model of myocardial infarction 期刊论文 JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 266, 页码: 10 作者:  Yu, Feng;  Yu, Yue;  Tian, Saisai;  Zhou, Yanting;  Chen, Xiangling 收藏  |  浏览/下载：36/0  |  提交时间：2021/05/24 Shexiang baoxin pill  Cardiovascular disease  LC-MS/MS  Quantitative proteomics  Energy metabolism   Uncovering kappa-opioid receptor agonist-induced PAK1/2 phosphorylation by quantitative phosphoproteomics 期刊论文 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 516, 期号: 1, 页码: 320-326 作者:  Wu, Jianhong;  Jiang, Qinghui;  Zhu, Hongwen;  Zhou, Yanting;  Lu, Dayun 收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01 Dimethyl labeling  Kappa-opioid receptor  Kinase-substrate network  p21-activated kinases  Quantitative phosphoproteomics   Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics 期刊论文 JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 6, 页码: 2654-2665 作者:  Chen, Xiangling;  Lu, Dayun;  Gao, Jing;  Zhu, Hongwen;  Zhou, Yanting 收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 deubiquitinase  USP9X  NFX1-123  SILAC  quantitative proteomics   Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response 期刊论文 CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 3, 页码: 344-353 作者:  Liu, Peng;  Chen, Xiangling;  Zhu, Jianming;  Li, Bo;  Chen, Zhaoqiang 收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01 autophagy  Hsp72  Hsp90 inhibitor  triazines  antitumor activity   aberrantmodulationofribosomalproteins6phosphorylationconfersacquiredresistancetomapkpathwayinhibitorsinbrafmutantmelanoma 期刊论文 中国药理学报英文版, 2019, 卷号: 040, 期号: 002, 页码: 268 作者:  Mingzhao Gao;  Hongbin Wang;  Xiangling Chen;  Wenting Cao;  Li Fu 收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01 BRAF-mutant  melanoma  MAPK  pathway  inhibitors  acquired  resistance  P70S6K  RSK  rpS6  G1/G0  phase  arrest  mTOR  inhibitor   A novel USP9X substrate TTK contributes to tumorigenesis in non-small-cell lung cancer 期刊论文 THERANOSTICS, 2018, 卷号: 8, 期号: 9, 页码: 2348-2360 作者:  Chen, Xiangling;  Yu, Chengli;  Gao, Jing;  Zhu, Hongwen;  Cui, Binghai 收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 non-small cell lung cancer (NSCLC)  quantitative proteomics  deubiquitinase  USP9X  TTK   DCZ3112, a novel Hsp90 inhibitor, exerts potent antitumor activity against HER2-positive breast cancer through disruption of Hsp9O-Cdc37 interaction 期刊论文 CANCER LETTERS, 2018, 卷号: 434, 页码: 70-80 作者:  Chen, Xiangling;  Liu, Peng;  Wang, Quanren;  Li, Yun;  Fu, Li 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Cdc37  DCZ3112  Geldanamycin  Hsp90  HER2-positive breast cancer   Pharmacologic characterization of SHR8443, a novel dual inhibitor of phosphatidylinositol 3-kinase and mammalian target of rapamycin 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 64, 页码: 107977-107990 作者:  Xie, Chengying;  Chen, Xiangling;  Zheng, Mingyue;  Liu, Xiaohong;  Wang, Hongbin 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 BEZ235  drug resistance  mTOR  PI3K  SHR8443   Deep Phosphoproteomic Measurements Pinpointing Drug Induced Protective Mechanisms in Neuronal Cells 期刊论文 FRONTIERS IN PHYSIOLOGY, 2016, 卷号: 7 作者:  Yu, Chengli;  Gao, Jing;  Zhou, Yanting;  Chen, Xiangling;  Xiao, Ruoxuan 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 phosphoproteomics  Alzheimer's disease  drug effect  mass spectrometry  neutronal cells