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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Molecular basis of ligand recognition and activation of human V2 vasopressin receptor 期刊论文 CELL RESEARCH, 2021, 页码: 3 作者:  Zhou, Fulai;  Ye, Chenyu;  Ma, Xiaomin;  Yin, Wanchao;  Croll, Tristan I. 收藏  |  浏览/下载：17/0  |  提交时间：2021/05/24 Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease 期刊论文 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 4, 页码: 646-666 作者:  Li, Xiaokang;  Lu, Jian;  Xu, Yixiang;  Wang, Jiaying;  Qiu, Xiaoxia 收藏  |  浏览/下载：46/0  |  提交时间：2020/07/01 Alzheimer's disease  Autophagy  Nitazoxanide  beta-amyloid  Tau protein   Development of Novel N-hydroxypyridone Derivatives as Potential Anti-Ischemic Stroke Agents 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 3, 页码: 1051-1067 作者:  Hu, Linghao;  Feng, Hongxuan;  Zhang, Hongguang;  Yu, Songda;  Zhao, Qinyuan 收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents 期刊论文 ACS chemical neuroscience, 2018 作者:  Xu, Yixiang;  Zhang, Jian;  Wang, Huan;  Mao, Fei;  Bao, Keting 收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08 Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125 作者:  Liu, Wenwen;  Wang, Huan;  Li, Xiaokang;  Xu, Yixiang;  Zhang, Jian 收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08 Depression  Cognitive impairment  Multitarget-directed ligand  5-HT1A agonist  5-HT reuptake inhibition  ChE inhibition   Novel Tadalafil Derivatives Ameliorates Scopolamine-Induced Cognitive Impairment in Mice via Inhibition of Acetyicholinesterase (AChE) and Phosphodiesterase 5 (PDE5) 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 7, 页码: 1625-1636 作者:  Ni, Wei;  Wang, Huan;  Li, Xiaokang;  Zheng, Xinyu;  Wang, Manjiong 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 Multifunctional agents  AChE inhibitors  PDE5 inhibitors  Alzheimer's disease   Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant Staphylococcus aureus 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 3, 页码: 233-237 作者:  Ni, Shuaishuai;  Li, Baoli;  Chen, Feifei;  Wei, Hanwen;  Mao, Fei 收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Virulence factor  pigment  multidrug resistant MRSA  CrtN inhibitor   Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345 作者:  Mao, Fei;  Wang, Huan;  Ni, Wei;  Zheng, Xinyu;  Wang, Manjiong 收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 Alzheimer's disease  drug repositioning  dual-target inhibitor  AChE inhibition  PDE5 inhibition   Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721 作者:  Li, Xiaokang;  Wang, Huan;  Xu, Yixiang;  Liu, Wenwen;  Gong, Qi 收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Alzheimer's disease  depression  multitarget-directed ligand  ChE inhibition  5-HT1A agonist  5-HT reuptake inhibition   Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 19, 页码: 8145-8159 作者:  Ni, Shuaishuai;  Wei, Hanwen;  Li, Baoli;  Chen, Feifei;  Liu, Yifu 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08