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CORC

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Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis 期刊论文
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:  Liu, Ping;  Cong, Xiaoji;  Liao, Shengjie;  Jia, Xinglong;  Wang, Xiaomin
收藏  |  浏览/下载：79/0  |  提交时间：2021/08/17
Reply to: Binding site for MDL-801 on SIRT6 期刊论文
NATURE CHEMICAL BIOLOGY, 2021, 页码: 5
作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin
收藏  |  浏览/下载：64/0  |  提交时间：2021/05/24
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
收藏  |  浏览/下载：35/0  |  提交时间：2021/05/24
SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways 期刊论文
CANCER CELL, 2020, 卷号: 38, 期号: 3, 页码: 350-+
作者:  Yuan, Huairui;  Han, Ying;  Wang, Xuege;  Li, Ni;  Liu, Qiuli
收藏  |  浏览/下载：32/0  |  提交时间：2020/12/24
EZH2 inhibitors abrogate upregulation of trimethylation of H3K27 by CDK9 inhibitors and potentiate its activity against diffuse large B-cell lymphoma 期刊论文
HAEMATOLOGICA, 2020, 卷号: 105, 期号: 4, 页码: 1021-1031
作者:  Xie, Shao;  Wei, Fan;  Sun, Yi-ming;  Gao, Ying-lei;  Pan, Lu-lu
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:  Jin, Nan;  Bi, Aiwei;  Lan, Xiaojing;  Xu, Jun;  Wang, Xiaomin
收藏  |  浏览/下载：61/0  |  提交时间：2020/07/01
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma 期刊论文
NATURE, 2019, 卷号: 567, 期号: 7747, 页码: 257-+
作者:  Jiang, Ying;  Sun, Aihua;  Zhao, Yang;  Ying, Wantao;  Sun, Huichuan
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01
Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文
Cancer Biology and Medicine, 2019, 卷号: 16, 期号: 1, 页码: 66
作者:  Wang Yuxiang;  Li Xian;  Liu Xueling;  Chen Yi;  Yang Chunhao
收藏  |  浏览/下载：14/0  |  提交时间：2020/12/24
PI3Kα  CDK4/6  KRAS  NSCLC  CYH33  
simultaneousinhibitionofpi3kandcdk46synergisticallysuppresseskrasmutatednonsmallcelllungcancer 期刊论文
癌症生物学与医学英文版, 2019, 卷号: 016, 期号: 001, 页码: 66
作者:  Yuxiang Wang;  Xian Li;  Xueling Liu;  Yi Chen;  Chunhao Yang
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01
PI3Kα  CDK4/6  KRAS  NSCLC  CYH33  
Identification of a cellularly active SIRT6 allosteric activator 期刊论文
NATURE CHEMICAL BIOLOGY, 2018, 卷号: 14, 期号: 12, 页码: 1118-+
作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin
收藏  |  浏览/下载：91/0  |  提交时间：2019/01/08

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