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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433 作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui 收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04 Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030 作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li 收藏  |  浏览/下载：114/0  |  提交时间：2021/05/24 Morphinans  arylacetamidyl substituent  kappa opioid receptor modulators  structure-activity relationships   A phase II randomized trial of sodium oligomannate in Alzheimer's dementia 期刊论文 ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10 作者:  Wang, Tao;  Kuang, Weihong;  Chen, Wei;  Xu, Wenwei;  Zhang, Liming 收藏  |  浏览/下载：63/0  |  提交时间：2020/12/21 Sodium oligomannate  Efficacy  Safety  Alzheimer's disease  Clinical trial   A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2020, 卷号: 12, 期号: 1 作者:  Wang,Tao;  Kuang,Weihong;  Chen,Wei;  Xu,Wenwei;  Zhang,Liming 收藏  |  浏览/下载：70/0  |  提交时间：2020/12/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase 期刊论文 NUCLEIC ACIDS RESEARCH, 2020, 卷号: 48, 期号: 5, 页码: 2709-2722 作者:  Nguyen, Phuong D. M.;  Zheng, Jie;  Gremminger, Thomas J.;  Qiu, Liming;  Zhang, Dong 收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070 作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui 收藏  |  浏览/下载：93/0  |  提交时间：2020/07/01