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科研机构
上海药物研究所 [11]
内容类型
期刊论文 [11]
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2017 [1]
2015 [1]
2014 [2]
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Taxodikaloids A and B, Two Dimeric Abietane-Type Diterpenoids from Taxodium ascendens Possessing an Oxazoline Ring Linkage
期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 3, 页码: 556-559
作者:
Huang, Xing-Hao
;
Tao, Ling-Xue
;
Ke, Chang-Qiang
;
Tang, Chunping
;
Zhang, Hai-Yan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Discovery, stereospecific characterization and peripheral modification of 1-(pyrrolidin-1-ylmethyl)-2-[(6-chloro-3-oxo-indan)-formyl]-1,2,3,4-tetrahydroisoquinolines as novel selective kappa opioid receptor agonists
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 卷号: 13, 期号: 20, 页码: 5656-5673
作者:
Gan, Zong-Jie
;
Wang, Yu-Hua
;
Xu, Yun-Gen
;
Guo, Ting
;
Wang, Jun
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Pharmacological characterization and therapeutic potential for the treatment of opioid abuse with ATPM-ET, an N-ethyl substituted aminothiazolomorphinan with kappa agonist and mu agonist/antagonist activity
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2014, 卷号: 740, 页码: 455-463
作者:
Sun, Jian-Feng
;
Wang, Yu-Hua
;
Chai, Jing-Rui
;
Li, Fu-Ying
;
Hang, Ai
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
kappa against and mu agonistfantagonist
Antinociception
Sedation
CPP
Heroin self-administration
Reinstatement of drug seeking behavior
Chemical Constituents from the Heartwood of Haematoxylon campechianum as Protein Tyrosine Kinase Inhibitors
期刊论文
CHEMISTRY & BIODIVERSITY, 2014, 卷号: 11, 期号: 5, 页码: 776-783
作者:
Lin, Li-Gen
;
Xie, Hua
;
Wang, Yi-Tao
;
Ding, Jian
;
Ye, Yang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Haematoxylon campechianum
Protein tyrosine kinases (PTKs)
Epihematoxylol B
Homoisoflavonoids
Hematoxylol B
10-O-methyl-
Kinase insert domain receptor (KDR)
Extinction of Aversive Memories Associated with Morphine Withdrawal Requires ERK-Mediated Epigenetic Regulation of Brain-Derived Neurotrophic Factor Transcription in the Rat Ventromedial Prefrontal Cortex
期刊论文
JOURNAL OF NEUROSCIENCE, 2012, 卷号: 32, 期号: 40, 页码: 13763-13775
作者:
Wang, Wei-Sheng
;
Kang, Shuo
;
Liu, Wen-Tao
;
Li, Mu
;
Liu, Yao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Effects of ATPM-ET, a novel kappa agonist with partial mu activity, on morphine-induced physical dependence and behavior sensitization in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2010, 卷号: 31, 期号: 12, 页码: 1547-1552
作者:
Sun, Jian-feng
;
Wang, Yu-hua
;
Li, Fu-ying
;
Lu, Gang
;
Tao, Yi-min
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
behavioral sensitization
mu opioid receptors
morphine
kappa opioid receptors
physical dependence
addiction
Highly selective and potent mu opioid ligands by unexpected substituent on morphine skeleton
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 卷号: 20, 期号: 1, 页码: 418-421
作者:
Li, Wei
;
Tao, Yi-Min
;
Tang, Yun
;
Xu, Xue-Jun
;
Chen, Jie
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
mu Opioid agonists
Selective ligands
Oripavines
Pharmacological Characterization of ATPM [(-)-3-Amino-thiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a Novel Mixed kappa-Agonist and mu-Agonist/-Antagonist That Attenuates Morphine Antinociceptive Tolerance and Heroin Self-Administration Behavior
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2009, 卷号: 329, 期号: 1, 页码: 306-313
作者:
Wang, Yu-Jun
;
Tao, Yi-Min
;
Li, Fu-Ying
;
Wang, Yu-Hua
;
Xu, Xue-Jun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Role of Src in ligand-specific regulation of delta-opioid receptor desensitization and internalization
期刊论文
JOURNAL OF NEUROCHEMISTRY, 2009, 卷号: 108, 期号: 1, 页码: 102-114
作者:
Hong, Min-Hua
;
Xu, Chi
;
Wang, Yu-Jun
;
Ji, Jing-Li
;
Tao, Yi-Min
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
beta-arrestin
delta-opioid receptor
desensitization
GRK2
internalization
Src
LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2008, 卷号: 584, 期号: 2-3, 页码: 306-311
作者:
Tao, Yi-Min
;
Li, Qing-Lin
;
Zhang, Cong-Fen
;
Xu, Xue-Jun
;
Chen, Jie
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
kappa-opioid receptor
LPK-26
(-)U50,488H
morphine
physical dependence
antinociception
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