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科研机构
上海药物研究所 [79]
内容类型
期刊论文 [79]
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2021 [4]
2020 [3]
2019 [1]
2018 [6]
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A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies
期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+
作者:
Liu, Zhiwei
;
Liu, Yingluo
;
Qian, Lili
;
Jiang, Shangwen
;
Gai, Xiameng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/01
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors
Stimuli-activatable nanomaterials for phototherapy of cancer
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 4, 页码: 11
作者:
Zhou, Mengjiao
;
Liu, Xiao
;
Chen, Fangmin
;
Yang, Lili
;
Yuan, Minjian
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2021/06/11
cancer treatment
photodynamic therapy
photothermal therapy
intelligent nanomaterials
stimuli-responsiveness
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:
Wang, Lei
;
Zhu, Xi
;
Li, Lili
;
Li, Lin
;
Fu, Li
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/06/11
PARP
DNA damage
hematologic toxicity
beta-glucuronidase
tumor selectivity
Intrinsic stability study of L-alpha-glycerylphosphorylcholine with HPLC method development and validation
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 188, 页码: 6
作者:
Zhao, Hongwei
;
Sun, Ling
;
Chen, Huanhuan
;
Xiang, Lili
;
Chen, Dongying
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/24
L-alpha-Glycerylphosphorylcholine
Phosphate ester bond
Forced degradation
HPLC
Intrinsic stability
Kinetics study
Biomimetic metal-organic nanoparticles prepared with a 3D-printed microfluidic device as a novel formulation for disulfiram-based therapy against breast cancer
期刊论文
APPLIED MATERIALS TODAY, 2020, 卷号: 18, 页码: 12
作者:
Chang, Ya
;
Jiang, Jizong
;
Chen, Wu
;
Yang, Wen
;
Chen, Lili
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
Biomimetic delivery
Metal-organic nanoparticle
Disulfiram
Copper diethyldithiocarbamate
Microfluidic
Breast cancer
A Sphingosine-1-Phosphate Modulator Ameliorates Polycystic Kidney Disease in Han:SPRD Rats
期刊论文
AMERICAN JOURNAL OF NEPHROLOGY, 2020, 卷号: 51, 期号: 1, 页码: 1-10
作者:
Li, Xin
;
Wu, Ming
;
Chen, Limin
;
Lu, Junyan
;
Li, Guo
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
FTY720
Sphingosine-1-phosphate
Cordyceps sinensis
Autosomal dominant polycystic kidney disease
Inflammation
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
Liquiritigenin and liquiritin alleviated MCT-induced HSOS by activating Nrf2 antioxidative defense system
期刊论文
Toxicology and applied pharmacology, 2018, 卷号: 355, 页码: 18-27
作者:
Huang, Zhenlin
;
Sheng, Yuchen
;
Chen, Minwei
;
Hao, Zhanxia
;
Hu, Feifei
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1α promoter
期刊论文
Metabolism: clinical and experimental, 2018, 卷号: 85, 页码: 126-138
作者:
Xu, Xin
;
Shi, Xiaofan
;
Chen, Yidi
;
Zhou, Tingting
;
Wang, Jiaying
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2019/01/08
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