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科研机构
上海药物研究所 [16]
内容类型
期刊论文 [16]
发表日期
2021 [3]
2020 [2]
2019 [2]
2018 [5]
2016 [3]
2012 [1]
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专题:上海药物研究所
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The Novel Chinese Medicine JY5 Formula Alleviates Hepatic Fibrosis by Inhibiting the Notch Signaling Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 15
作者:
Fu, Yadong
;
Xiao, Zhun
;
Tian, Xiaoting
;
Liu, Wei
;
Xu, Zhou
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/01/04
traditional Chinese medicine
JY5 formula
fuzheng huayu
hepatic fibrosis
notch signaling pathway
Systematic investigation on the anti-rheumatoid arthritis material basis and mechanism of Juan Bi Tang. Part 1: Integrating metabolic profiles and network pharmacology
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 202, 页码: 11
作者:
Li, Jiajia
;
Li, Lei
;
Wang, Yangyang
;
Zhao, Yuxuan
;
Hu, Pei
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/08/17
Juanbi-Tang (JBT)
Rheumatoid arthritis (RA)
Metabolites
Mass
Network pharmacology
Molecular docking
Identification of the absorbed ingredients and metabolites in rats after an intravenous administration of Tanreqing injection using high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16
作者:
Xie, Like
;
Wang, Yangyang
;
Yin, Hao
;
Li, Jiajia
;
Xu, Zhou
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/05/24
COVID‐
19
metabolic profiles
quadrupole time‐
of‐
flight mass spectrometry
Tanreqing injection
traditional Chinese medicine
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Hu, Pei
;
Yu, Yanyan
;
Li, Zhixiong
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2020/12/21
Phellodendri Chinensis cortex
Hepatic disposition
Pharmacokinetics
Berberine
Metabolites
Hepatic gluconeogenesis
Systematic investigation on the chemical basis of anti-NAFLD Qushi Huayu Fang. Part 1: A study of metabolic profiles in vivo and in vitro by high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 15
作者:
Liu, Huan
;
Sun, Zhaolin
;
Tian, Xiaoting
;
Feng, Qin
;
Guo, Ziqiong
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
HPLC-Q-TOF
intestinal bacteria
liver
metabolism
Qushi Huayu Fang
Determining the protective effects of Yin-Chen-Hao Tang against acute liver injury induced by carbon tetrachloride using 16S rRNA gene sequencing and LC/MS-based metabolomics
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 174, 页码: 567-577
作者:
Liu, Fang
;
Sun, Zhaolin
;
Hu, Pei
;
Tian, Qiang
;
Xu, Zhou
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Yin-Chen-Hao Tang
Liver injury
Metabolomics
Gut microbiota
LC-MS
Gene sequencing
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:
Tian, Xiaoting
;
Liu, Fang
;
Li, Zhixiong
;
Lin, Yunfei
;
Liu, Huan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
berberine
timosaponin B2
diabetes
combination treatments
drug-drug interaction
metabolites
hepatic metabolism
intestinal absorption
Absorption, Metabolism, and Pharmacokinetics Profiles of Norathyriol, an Aglycone of Mangiferin, in Rats by HPLC-MS/MS
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 卷号: 66, 期号: 46, 页码: 12227-12235
作者:
Guo, Xiaozhen
;
Cheng, Mingcang
;
Hu, Pei
;
Shi, Zhangpeng
;
Chen, Shuoji
收藏
  |  
浏览/下载:266/0
  |  
提交时间:2019/01/08
norathyriol
pharmacokinetics
bioavailability
metabolism
HPLC-MS/MS
Simultaneous determination of eight bioactive compounds by LC-MS/MS and its application to the pharmacokinetics, liver first-pass effect, liver and brain distribution of orally administrated Gouteng-Baitouweng (GB) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 卷号: 1084, 页码: 122-131
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Chen, Mingcang
;
Hu, Pei
;
Liu, Fang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Gouteng-Baitouweng
LC-MS/MS
Pharmacokinetics
Liver
Brain
liver first-pass effect
A sensitive HPLC-MS/MS method for the simultaneous determination of anemoside B4, anemoside A3 and 23-hydroxybetulinic acid: Application to the pharmacokinetics and liver distribution of Pulsatilla chinensis saponins
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2018, 卷号: 32, 期号: 3
作者:
Guo, Xiaozhen
;
Xie, Yang
;
Lian, Shan
;
Li, Zhixiong
;
Gao, Yu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
23-hydroxybetulinic acid
HPLC-MS
MS
liver distribution
pharmacokinetics
Pulsatilla chinensis saponins
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