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Compounds 1-oxo -1h-(phthalazin or isoquinoline)-2-yl substituted, inhibitors of the tyrosine kinase bruton' s (btk); pharmaceutical composition; a method for the treatment of autoimmune inflammatory disease state y/o, arthritis or asthma [...] ; and use for treating a disease state inflammatory autoimmune y/o. 专利
作者:  JAIME-FIGUEROA SAUL;  LOPEZ-TAPIA FRANCISCO JAVIER;  LOU YAN;  BROTHERTON-PLEISS CHRISTINE;  OWENS TIMOTHY D
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Compounds derived from 6-(2-hydroxymethyl-phenyl)-2-methyl -2 H-pyridazin-3-one, inhibitors of the tyrosine kinase bruton' s (btk); pharmaceutical composition; method for treating an inflammatory autoimmune y/o, rheumatoid arthritis or asthma; and their use to treat autoimmune y/o an inflammatory condition. 专利
作者:  LOU YAN;  BERTHEL STEVEN JOSEPH;  BILLEDEAU ROLAND J;  BROTHERTON CHRISTINE E;  FIROOZNIA FARIBORZ
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