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浏览/检索结果: 共22条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo 收藏  |  浏览/下载：42/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11 作者:  Fan, Shijie;  Yue, Liyan;  Wan, Wei;  Zhang, Yuanyuan;  Zhang, Bidong 收藏  |  浏览/下载：80/0  |  提交时间：2021/12/16 covalent modification  probes  proteome  LC3  post-translational modification   Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11 作者:  Li, Bo;  Li, Heng;  Zhu, Zhengdan;  Xiang, Caigui;  Xu, Zhijian 收藏  |  浏览/下载：99/0  |  提交时间：2021/11/04 Anti-inflammatory activity  TNF alpha  ER beta  IBD Arylisoquinolones   Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong 收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16 Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson 期刊论文 FITOTERAPIA, 2021, 卷号: 154, 页码: 5 作者:  Wang, Ai-Zhu;  Fang, Qiang-Qiang;  Feng, Tong-Tong;  Wei, Ren-Jie;  Jiang, Kun 收藏  |  浏览/下载：38/0  |  提交时间：2021/12/01 Hypericum acmosepalum  Clusiaceae  Xanthones  Antioxidant  Cytotoxicity   An Atom-Economic Inverse Solid-Phase Peptide Synthesis Using Bn or BcM Esters of Amino Acids 期刊论文 ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7571-7574 作者:  Li, Jian;  Zhu, Yue;  Liu, Bo;  Tang, Feng;  Zheng, Xing 收藏  |  浏览/下载：9/0  |  提交时间：2021/12/01 BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14 作者:  Feng, Mei;  Wu, Zhongen;  Zhou, Yan;  Wei, Zhuang;  Tian, Enming 收藏  |  浏览/下载：29/0  |  提交时间：2021/11/04 Allicin inclusions with alpha-cyclodextrin effectively masking its odor: Preparation, characterization, and olfactory and gustatory evaluation 期刊论文 JOURNAL OF FOOD SCIENCE, 2021, 页码: 11 作者:  Zhou, Yong;  Feng, Jing;  Peng, Hui;  Guo, Tao;  Xiao, Jian 收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04 allicin  inclusion complex  odor masking  stability  alpha-cyclodextrin   Competitive CatSper Activators of Progesterone from Rhynchosia volubilis 期刊论文 PLANTA MEDICA, 2021, 页码: 10 作者:  Xiang, Jin;  Kang, Hang;  Li, Hong-Gang;  Shi, Yu-Long;  Zhang, Ya-Li 收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04 Leguminosae  Rhynchosia volubilis  CatSper  prenylated isoflavonoids  rhynchones A - E   Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya 收藏  |  浏览/下载：86/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators