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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Zou, Hui-xi;  Zhang, Yu-feng;  Zhong, Da-fang;  Jiang, Yong;  Liu, Fei 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/04 furmonertinib  autoinduction  food effect  alkaline phosphatase  body weight  pharmacokinetics  modeling and simulation  NSCLC   Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers 期刊论文 CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273 作者:  Chen, Zhen-dong;  Chen, Qian;  Zhu, Yun-ting;  Zhang, Yi-fan;  Zhan, Yan 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/04 henagliflozin  food effects  mass balance  pharmacokinetics  SGLT-2 inhibitor   Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu 收藏  |  浏览/下载：22/0  |  提交时间：2021/08/17 furmonertinib (alflutinib  AST2818)  quantitative proteomics  sandwich-cultured human hepatocytes   Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7 作者:  Pan, Lu-lu;  Chen, Tao;  Hui, Min;  Wang, Shuo;  Fu, Li 收藏  |  浏览/下载：131/0  |  提交时间：2021/05/24 LC-MS/MS  Forsythin  Aglycone glucuronide  Aglycone sulfate  Pharmacokinetics   Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Meng, Jian;  Zhang, Hua;  Bao, Jing-jing;  Chen, Zhen-dong;  Liu, Xiao-yun 收藏  |  浏览/下载：69/0  |  提交时间：2021/06/11 metabolism  mass balance  distribution  covalent binding  furmonertinib   Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Meng, Jian;  Zhang, Hua;  Bao, Jing-jing;  Chen, Zhen-dong;  Liu, Xiao-yun 收藏  |  浏览/下载：72/0  |  提交时间：2021/06/11 metabolism  mass balance  distribution  covalent binding  furmonertinib   Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration 期刊论文 CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409 作者:  Zhang, Yi-fan;  Liu, Yan-mei;  Yu, Chen;  Wang, Ya-ting;  Zhan, Yan 收藏  |  浏览/下载：69/0  |  提交时间：2021/05/24 diabetes  henagliflozin  pharmacodynamics  pharmacokinetics  SGLT-2 inhibitors   Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers 期刊论文 INVESTIGATIONAL NEW DRUGS, 2021, 页码: 8 作者:  Zhu, Yun-ting;  Zhang, Yi-fan;  Jiang, Jin-fang;  Yang, Yong;  Guo, Li-xia 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 Alflutinib  Rifampicin  CYP3A4  AST5902  Drug-drug interaction