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浏览/检索结果: 共48条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters 期刊论文 CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256 作者:  Dong, Lei;  Zhang, Min-Yu;  Han, Hai-Hao;  Zang, Yi;  Chen, Guo-Rong 收藏  |  浏览/下载：31/0  |  提交时间：2022/01/18 Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14 作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue 收藏  |  浏览/下载：21/0  |  提交时间：2022/01/18 Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence 期刊论文 NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089 作者:  Bai, Xiangd;  Wang, Hanchen;  Ma, Liya;  Xu, Yongchao;  Gan, Jiefeng 收藏  |  浏览/下载：52/0  |  提交时间：2022/01/18 Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong 收藏  |  浏览/下载：77/0  |  提交时间：2022/01/04 idiopathic pulmonary fibrosis  DDRs  kinase inhibitor  indazole derivatives  XBLJ-13  nintedanib  bleomycin-induced pulmonary fibrosismouse model   Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGF beta signaling 期刊论文 ONCOGENE, 2021, 页码: 10 作者:  Kong, Ya;  Zhang, Yutian;  Wang, Hanlin;  Kan, Weijuan;  Guo, Haoran 收藏  |  浏览/下载：51/0  |  提交时间：2022/01/04 Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Chen, Cheng;  Ren, Yong-mei;  Zhu, Jian-zhong;  Chen, Jia-li;  Feng, Zhe-ling 收藏  |  浏览/下载：56/0  |  提交时间：2022/01/04 Ainsliadimer C  interleukin-1 beta  macrophages  NLRP3 inflammasome  Sirtuin 1  adipose tissue inflammation  obesity  metabolic disorders  EX-527  dexamethasone   Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13 作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun 收藏  |  浏览/下载：31/0  |  提交时间：2021/12/01 2,5-diphenyl-1,3,4-oxadiazole derivatives  SHP2  Inhibitors  Structure-activity relationships (SAR)   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04 5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   Temperature-Controlled Divergent Synthesis of Tetrasubstituted Alkenes and Pyrrolo[1,2-a]indole Derivatives via Iridium Catalysis 期刊论文 ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 页码: 14 作者:  Liu, Siyu;  Mao, Hui;  Qiao, Jin;  Zhang, Xiaoning;  Lu, Yangbin 收藏  |  浏览/下载：73/0  |  提交时间：2021/11/04 Iridium  C-H activation  [3+2] annulation  Tetrasubstituted alkene  pyrrolo[1,2-a]indole