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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine 期刊论文 LIFE SCIENCES, 2021, 卷号: 287, 页码: 14 作者:  Xue, Yaru;  Ren, Xuelian;  Zhu, Zhengdan;  Lei, Peng;  Liu, Mengling 收藏  |  浏览/下载：39/0  |  提交时间：2022/01/18 3-n-butylphthalide  Hepatotoxicity  Oxidative stresses  Covalent protein modification  Drug-drug interaction   GADD45 beta stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation 期刊论文 PHARMACOLOGICAL RESEARCH, 2021, 卷号: 173, 页码: 11 作者:  Dong, Yunxia;  Ma, Ningning;  Fan, Lei;  Yuan, Luyang;  Wu, Qian 收藏  |  浏览/下载：61/0  |  提交时间：2021/12/16 Non-alcoholic fatty liver disease  GADD45 beta  HSP72  Lipid accumulation  Insulin resistance   Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya 收藏  |  浏览/下载：86/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators   New PCSK9 inhibitor miR-552-3p reduces LDL-C via enhancing LDLR in high fat diet-fed mice 期刊论文 PHARMACOLOGICAL RESEARCH, 2021, 卷号: 167, 页码: 13 作者:  Ma, Ningning;  Fan, Lei;  Dong, Yunxia;  Xu, Xiaoding;  Yu, Chuwei 收藏  |  浏览/下载：48/0  |  提交时间：2021/08/17 PCSK9  Hyperlipidemia  MiR-552-3p  3 '-UTR  Promoter   A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Ren, Peng-xuan;  Shang, Wei-juan;  Yin, Wan-chao;  Ge, Huan;  Wang, Lin 收藏  |  浏览/下载：85/0  |  提交时间：2021/06/11 SARS-CoV-2 inhibitors  RdRp  host ribosome  Virus RNA   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：148/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Liu, Yong-zhen;  Lu, Heng-lei;  Qi, Xin-ming;  Xing, Guo-zhen;  Wang, Xin 收藏  |  浏览/下载：72/0  |  提交时间：2021/05/24 aristolochic acid I  glutathione S-transferase placental form-positive foci  clonal expansion  hepatocellular carcinoma  medium-term rat liver bioassay  DNA adducts   miR-552-3p modulates transcriptional activities of FXR and LXR to ameliorate hepatic glycolipid metabolism disorder 期刊论文 JOURNAL OF HEPATOLOGY, 2021, 卷号: 74, 期号: 1, 页码: 8-19 作者:  Fan, Lei;  Lai, Rongtao;  Ma, Ningning;  Dong, Yunxia;  Li, Yu 收藏  |  浏览/下载：41/0  |  提交时间：2021/05/24 miR-552-3p  Transcriptional gene regulation  Intranuclear miRNAs  Glycolipid metabolic disease  NR1 subfamily