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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic 期刊论文 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402 作者:  Jiao, Shang;  Guan, Dongliang;  Xu, Lili;  Liu, Bo;  Shi, Weiwei 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/18 glycopeptide antibiotics  impurity  analytical method  process optimization and development   An Atom-Economic Inverse Solid-Phase Peptide Synthesis Using Bn or BcM Esters of Amino Acids 期刊论文 ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7571-7574 作者:  Li, Jian;  Zhu, Yue;  Liu, Bo;  Tang, Feng;  Zheng, Xing 收藏  |  浏览/下载：9/0  |  提交时间：2021/12/01 Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng 收藏  |  浏览/下载：93/0  |  提交时间：2021/11/04 multiple myeloma  HDAC inhibitor  bisthianostat  pharmacodynamics  pharmacokinetics  phase 1a clinical trial  antitumor drug   A facile method for vancomycin C-terminus functionalization and derivatization through hydrazide 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 页码: 6 作者:  Hu, Yu;  Zou, Xiangman;  Shi, Weiwei;  Ma, Chenhui;  Chen, Feifei 收藏  |  浏览/下载：17/0  |  提交时间：2021/08/17 Vancomycin C-terminus modification  Hydrazide derivatives  Native Chemical Ligation  Antibacterial activity   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：149/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Ren, Yu-ran;  Ye, Yang-liang;  Feng, Ying;  Xu, Ti-fei;  Shen, Yu 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 SL010110  gluconeogenesis  primary mouse hepatocytes  PEPCK1  acetylation  degradation   Anti-nociceptive, anti-inflammatory and anti-arthritic activities of pregnane glycosides from the root bark of Periploca sepium Bunge 期刊论文 JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 265, 页码: 12 作者:  Lin, Ze-min;  Liu, Yu-ting;  Huang, Yue-teng;  Yang, Xiao-qian;  Zhu, Feng-hua 收藏  |  浏览/下载：43/0  |  提交时间：2021/05/24 Periploca sepium Bunge  Pregnane glycosides  Anti-nociceptive activity  Anti-inflammatory activity  Anti-arthritic activity  Inflammatory arthritis   A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Liu, Yu-ting;  Ding, Hui-hua;  Lin, Ze-min;  Wang, Que;  Chen, Li 收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24 rheumatoid arthritis  BTK inhibitors  B cells  macrophages  RANKL  osteoclastogenesis