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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora 期刊论文 PLANTA MEDICA, 2021, 页码: 7 作者:  Lei, Chun;  Li, Ya-Nan;  Li, Jia-Nan;  Zhou, Yu-Bo;  Cui, Ming-Jun 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/16 Trewia nudiflora  Euphorbiaceae  maytansinoids  cytotoxicity  tubulin polymerization   Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433 作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui 收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04 Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Huang, He-ming;  Fan, Shi-jie;  Zhou, Xiao-ru;  Liu, Yan-jun;  Li, Xiao 收藏  |  浏览/下载：58/0  |  提交时间：2021/11/04 nonalcoholic steatohepatitis  inflammation  histone deacetylase inhibitor  givinostat  epigenetics   Stimuli-activatable nanomaterials for phototherapy of cancer 期刊论文 BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 4, 页码: 11 作者:  Zhou, Mengjiao;  Liu, Xiao;  Chen, Fangmin;  Yang, Lili;  Yuan, Minjian 收藏  |  浏览/下载：79/0  |  提交时间：2021/06/11 cancer treatment  photodynamic therapy  photothermal therapy  intelligent nanomaterials  stimuli-responsiveness   Acylphloroglucinol derivatives with ATP citrate lyase inhibitory activities from Syzygium oblatum Wall 期刊论文 PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 7 作者:  Huang, Jin-Chang;  Liu, Yi-Nan;  Tao, Yun-Hua;  Chen, Bai-Yu;  Lei, Chun 收藏  |  浏览/下载：25/0  |  提交时间：2021/08/17 Syzygium oblatum Wall  Myrtaceae  Acylphloroglucinols  Oblatones A-I  ATP citrate lyase   Determination of maytansinoids in Trewia nudiflora using QuEChERS extraction combined with HPLC 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7 作者:  Li, Ya-Nan;  Li, Jia-Nan;  Ouyang, Qin;  Zhou, Yu-Bo;  Lei, Chun 收藏  |  浏览/下载：44/0  |  提交时间：2021/05/24 Trewia nudiflora  QuEChERS method  Maytansinoids  HPLC   Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation 期刊论文 IMMUNITY, 2021, 卷号: 54, 期号: 4, 页码: 632-+ 作者:  Wang, Yan;  Fu, Zunyun;  Li, Xutong;  Liang, Yinming;  Pei, Siyu 收藏  |  浏览/下载：61/0  |  提交时间：2021/06/11 Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury 期刊论文 CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 7, 页码: 925-941 作者:  Liu, Yanjun;  Li, Jiacheng;  Liao, Liping;  Huang, Heming;  Fan, Shijie 收藏  |  浏览/下载：21/0  |  提交时间：2021/08/17 Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855 作者:  Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Ligand-Promoted Alkynylation of Aryl Ketones: A Practical Tool for Structural Diversity in Drugs and Natural Products 期刊论文 ACS CATALYSIS, 2021, 卷号: 11, 期号: 3, 页码: 1758-1764 作者:  Xu, Hui;  Ma, Biao;  Fu, Zunyun;  Li, Han-Yuan;  Wang, Xing 收藏  |  浏览/下载：17/0  |  提交时间：2021/05/24 alkynylation  Ar-C(O) cleavage  ligand  palladium  late-stage diversification