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浏览/检索结果: 共42条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo 收藏  |  浏览/下载：42/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity 期刊论文 ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22 作者:  Hu, Lin;  Chen, Fuxian;  Wu, Chao;  Wang, Jun;  Chen, Si-si 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/18 Dezocine as a potent analgesic: overview of its pharmacological characterization 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Ye, Rong-Rong;  Jiang, Shuang;  Xu, Xu;  Lu, Yan;  Wang, Yu-Jun 收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16 dezocine  opioid receptors  norepinephrine  serotonin transporter  postoperative pain  anesthesia   Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence 期刊论文 CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21 作者:  Zan, Gui-Ying;  Wang, Yu-Jun;  Li, Xue-Ping;  Fang, Jun-Fan;  Yao, Song-Yu 收藏  |  浏览/下载：46/0  |  提交时间：2021/12/16 Quantitative proteomic analysis uncovers inhibition of melanin synthesis by silk fibroin via MITF/tyrosinase axis in B16 melanoma cells 期刊论文 LIFE SCIENCES, 2021, 卷号: 284, 页码: 7 作者:  Wang, Yuqiu;  Duan, Tianbi;  Hong, Minhua;  Zhou, Yanting;  Huang, Hui 收藏  |  浏览/下载：38/0  |  提交时间：2021/11/04 Silk fibroin  Quantitative proteomics  Melanin  Microphthalmia-associated transcription factor  Tyrosinase   Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125 作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao 收藏  |  浏览/下载：36/0  |  提交时间：2022/01/04 A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文 MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+ 作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng 收藏  |  浏览/下载：27/0  |  提交时间：2021/12/01 Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219 作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu 收藏  |  浏览/下载：40/0  |  提交时间：2021/12/01 Hippo pathway  TEAD3  Covalent inhibitor  Palmitoylation inhibitor   Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK 期刊论文 CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263 作者:  Elksnis, Andris;  Schiffer, Tomas A.;  Palm, Fredrik;  Wang, Yun;  Cen, Jing 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/01 Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain 期刊论文 MOLECULAR BRAIN, 2021, 卷号: 14, 期号: 1, 页码: 22 作者:  Shao, Fang-bing;  Fang, Jun-fan;  Wang, Si-si;  Qiu, Meng-ting;  Xi, Dan-ning 收藏  |  浏览/下载：112/0  |  提交时间：2021/11/04 Chronic inflammatory pain  Anxiety-like behavior  GABAergic system  Anterior cingulate cortex  synaptic transmission