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浏览/检索结果: 共4条，第1-4条 帮助 限定条件 发表日期：2020     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, Synthesis, and Biological Activities of Novel Triazolothiadiazole Derivatives Linked with Amino Side Chain Containing Urea Group as DOT1L Inhibitors 期刊论文 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 8, 页码: 2450-2459 作者:  Liu Na;  Guo Siqi;  Liu Junfang;  Chen Yantao;  Xu Xiaoming 收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24 DOT1L inhibitor  triazolothiadiazole  triazolothiadiazine  nucleophilic substitution   Structural Modifications of the Triazolo-thiadiazole Derivatives as DOT1L Inhibitors and Their Activities 期刊论文 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 5, 页码: 1345-1354 作者:  Xu Xiaoming;  Guo Siqi;  Zhang Jing;  Chen Yantao;  Kang Yaqing 收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 DOT1L inhibitor  ttriazolo-thiadiazole  structural modification  hydrophobic substituent  structure-activity analysis   Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7 作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao 收藏  |  浏览/下载：17/0  |  提交时间：2020/03/18 Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation   The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020 作者:  Xu, Guowei;  Yang, Yaqing;  Yang, Yanming;  Song, Gao;  Li, Shanshan 收藏  |  浏览/下载：22/0  |  提交时间：2021/01/05