QQ客服 官方微博 反馈留言

浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor 期刊论文 CELL RESEARCH, 2020, 页码: 11 作者:  Sun, Wen;  Chen, Li-Nan;  Zhou, Qingtong;  Zhao, Li-Hua;  Yang, Dehua 收藏  |  浏览/下载：85/0  |  提交时间：2020/12/24 Structural basis for activation of the growth hormone-releasing hormone receptor 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10 作者:  Zhou, Fulai;  Zhang, Huibing;  Cong, Zhaotong;  Zhao, Li-Hua;  Zhou, Qingtong 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/21 An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy 期刊论文 NATURE BIOMEDICAL ENGINEERING, 2020, 页码: 16 作者:  Wang, Cong;  Sun, Wanbing;  Zhang, Jun;  Zhang, Jianping;  Guo, Qinghua 收藏  |  浏览/下载：28/0  |  提交时间：2020/12/21 Synthesis and Cytotoxic Activity of Novel C-23-Modified Asiatic Acid Derivatives 期刊论文 MOLECULES, 2020, 卷号: 25, 期号: 16, 页码: 20 作者:  Lu, Yi-hong;  Chen, Ming-cang;  Liu, Fang;  Xu, Zhou;  Tian, Xiao-ting 收藏  |  浏览/下载：13/0  |  提交时间：2020/12/24 asiatic acid  modification at C-23  intramolecular hydrogen bonding  cytotoxic activity   AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8 作者:  Sun, Shui-mei;  Xie, Zhi-fu;  Zhang, Yang-ming;  Zhang, Xin-wen;  Zhou, Chen-dong 收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24 adenosine 5 '-monophosphate-activated protein kinase  AMPK activator  C24  liver  triglycerides  cholesterol  VLDL  hypolipidemic drug  metabolic syndrome   Structural basis of GPBAR activation and bile acid recognition 期刊论文 NATURE, 2020, 页码: 29 作者:  Yang, Fan;  Mao, Chunyou;  Guo, Lulu;  Lin, Jingyu;  Ming, Qianqian 收藏  |  浏览/下载：46/0  |  提交时间：2020/12/24 Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27 作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X. 收藏  |  浏览/下载：103/0  |  提交时间：2020/07/01 embryonic ectoderm development  Enhancer of zeste homolog 2  fluorescence polarization  high-throughput screening  homogenous time-resolved fluorescence  inhibitor  polycomb repressive complex 2   Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma 期刊论文 JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908 作者:  Dong, Liang-qing;  Peng, Li-hua;  Ma, Li-jie;  Liu, Dong-bing;  Zhang, Shu 收藏  |  浏览/下载：63/0  |  提交时间：2020/07/01 Hepatocellular carcinoma  Tumor heterogeneity  Tumor microenvironment  Immunoediting  Neoantigen   An in vitro Fo''rster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10 作者:  Wang, Yu-zhe;  Liu, Xiao;  Way, George;  Madarha, Vipul;  Zhou, Qing-tong 收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01 SUMOylation inhibitor  WNN0605-F008  high-throughput screening  Ubc9  PIAS1  Fo''rster resonance energy transfer  surface plasmon resonance   Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407 作者:  Li, Zhiqiang;  Li, Xinzhi;  Su, Ming-Bo;  Gao, Li-Xin;  Zhou, Yu-Bo 收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01