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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy 期刊论文 CELL DEATH AND DIFFERENTIATION, 2020, 页码: 17 作者:  Guo, Huijie;  Pu, Mei;  Tai, Yusi;  Chen, Yuxiang;  Lu, Henglei 收藏  |  浏览/下载：56/0  |  提交时间：2020/12/24 Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文 ADVANCED SCIENCE, 2020, 页码: 13 作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen 收藏  |  浏览/下载：107/0  |  提交时间：2020/07/01 anti-metastasis activities  crystal structures  inhibitors  novel pockets  rho family proteins   2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文 CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287 作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian 收藏  |  浏览/下载：47/0  |  提交时间：2020/07/01 EGFR(C797S) mutant  SARs  2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidine  Clinical resistance  Fourth-generation inhibitors   Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14 作者:  Zhang, Xin;  Xu, Fang;  Tong, Linjiang;  Zhang, Tao;  Xie, Hua 收藏  |  浏览/下载：81/0  |  提交时间：2020/07/01 Epidermal growth factor receptor (EGFR)  Resistance  Proteolysis targeting chimera (PROTAC)  Protein degradation   MiR-629-5p promotes the invasion of lung adenocarcinoma via increasing both tumor cell invasion and endothelial cell permeability 期刊论文 ONCOGENE, 2020, 页码: 16 作者:  Li, Yu;  Zhang, Huibiao;  Fan, Lei;  Mou, Jiahui;  Yin, Yue 收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01 Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways 期刊论文 LIFE SCIENCES, 2020, 卷号: 243, 页码: 11 作者:  He, Wan;  Xu, Zhijian;  Song, Dongliang;  Zhang, Hui;  Li, Bo 收藏  |  浏览/下载：58/0  |  提交时间：2020/07/01 Diffuse large B-cell lymphoma  Rafoxanide  PTEN/PI3K/AKT  Apoptosis  DNA damage   Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-Neuroinflammatory Agents for Ischemic Stroke 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 卷号: 59, 期号: 6, 页码: 2429-2439 作者:  Gao, Cheng-Long;  Hou, Gui-Ge;  Liu, Jin;  Ru, Tong;  Xu, Ya-Zhou 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 anti-inflammatory  drug discovery  heterocycles  photoaffinity labeling  proteins   A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression 期刊论文 CANCER RESEARCH, 2020, 卷号: 80, 期号: 3, 页码: 536-548 作者:  Wang, Yingcong;  Huang, Jing;  Li, Bo;  Xue, Han;  Tricot, Guido 收藏  |  浏览/下载：54/0  |  提交时间：2020/07/01 Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292 作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan 收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 CBP bromodomain  small-molecule inhibitor  high-throughput screening  TR-FRET  molecular modeling  human leukemia MV4-11 cells   Nimesulide increases the aldehyde oxidase activity of humans and rats 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Zhou, Lei;  Pang, Xiao-yan;  Hou, Xiang-yu;  Liu, Lu;  Guo, Zi-tao 收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01 nimesulide  aldehyde oxidase  induction  methotrexate  hepatocytes  pharmacokinetics  drug interaction