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科研机构
上海药物研究所 [8]
内容类型
期刊论文 [8]
发表日期
2020 [8]
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发表日期:2020
专题:上海药物研究所
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Structure of SARS-CoV-2 main protease in the apo state
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020, 页码: 4
作者:
Zhou, Xuelan
;
Zhong, Fanglin
;
Lin, Cheng
;
Hu, Xiaohui
;
Zhang, Yan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/12/24
Revelation of AbfR in regulation of mismatch repair and energy metabolism in S. epidermidis by integrated proteomic and metabolomic analysis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 10
作者:
Gu, Lei
;
Liu, Xing
;
Wang, Yu-Qiu
;
Zhou, Yan-ting
;
Zhu, Hong-wen
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/21
Staphylococcus epidermidis
AbfR transcription factor
Oxidation-sensing regulator
Oxidative stress
TMT10-plex labelling
Antibiotic resistance regulator
Revelation of AbfR in regulation of mismatch repair and energy metabolism in S. epidermidis by integrated proteomic and metabolomic analysis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 10
作者:
Gu, Lei
;
Liu, Xing
;
Wang, Yu-Qiu
;
Zhou, Yan-ting
;
Zhu, Hong-wen
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Staphylococcus epidermidis
AbfR transcription factor
Oxidation-sensing regulator
Oxidative stress
TMT10-plex labelling
Antibiotic resistance regulator
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Shui-mei
;
Xie, Zhi-fu
;
Zhang, Yang-ming
;
Zhang, Xin-wen
;
Zhou, Chen-dong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
adenosine 5 '-monophosphate-activated protein kinase
AMPK activator
C24
liver
triglycerides
cholesterol
VLDL
hypolipidemic drug
metabolic syndrome
Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Yu, Yan-yan
;
Cui, Shi-chao
;
Zheng, Tian-nan
;
Ma, Hai-jian
;
Xie, Zhi-fu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
insulin resistance
sarsasapogenin
adipose tissue inflammation
macrophage-adipocyte crosstalk
IKK/NF-kappa B
JNK
Uncommon nornardosinane, seconeolemnane and related sesquiterpenoids from Xisha soft coral Litophyton nigrum
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 96, 页码: 8
作者:
Yang, Fan
;
Li, Song-Wei
;
Zhang, Jun
;
Liang, Lin-Fu
;
Lu, Yan-Hua
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Litophyton nigrum
Nornardosinane
Seconeolemnane
Cytotoxicity
Inhibitory activity
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