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CORC

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Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
收藏  |  浏览/下载：29/0  |  提交时间：2019/11/27
Discovery of 2-(4-Chloro-3-(trifluoromethyl)phenyl)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)acetamide (CHMFL-KIT-64) as a Novel Orally Available Potent Inhibitor against Broad-Spectrum Mutants of 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019
作者:  Yun Wu;  Beilei Wang;  Junjie Wang;  Qi S(亓爽);  Fengming Zou
收藏  |  浏览/下载：62/0  |  提交时间：2020/10/20
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen
收藏  |  浏览/下载：19/0  |  提交时间：2020/05/21
S-nitrosation impairs KLF4 activity and instigates endothelial dysfunction in pulmonary arterial hypertension. 期刊论文
Redox biology, 2019, 卷号: 21, 页码: 101099
作者:  Ban Yiqian;  Liu Yahan;  Li Yazi;  Zhang Yuying;  Xiao Lei
收藏  |  浏览/下载：26/0  |  提交时间：2019/11/19
Discovery of N-phenyl)-2-phenyl)acetamide as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
Journal of Medicinal Chemistry, 2019, 卷号: Vol.62 No.2, 页码: 875-892
作者:  Tingting Lu;  Jian Ge;  Tao Ren;  Wenchao Wang;  Junjie Wang
收藏  |  浏览/下载：36/0  |  提交时间：2019/04/24
Discovery of N-phenyl)-2-phenyl)acetamide as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: Vol.62 No.2, 页码: 875-892
作者:  Wang, Beilei;  Li, Feng;  Liu, Qingwang;  Hu, Zhenquan;  Liang, Xiaofei
收藏  |  浏览/下载：4/0  |  提交时间：2019/04/24
Down-regulation of miR-200c attenuates Angll-induced cardiac hypertrophy via targeting the MLCK-mediated pathway 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 4
作者:  Hu, Shan;  Cheng, Mian;  Guo, Xin;  Wang, Shun;  Liu, Beilei
收藏  |  浏览/下载：26/0  |  提交时间：2019/12/05
Astemizole-based turn-on fluorescent probes for imaging hERG potassium channel 期刊论文
MEDCHEMCOMM, 2019, 卷号: 10, 期号: 4, 页码: 513-516
作者:  Zhang, Xiaomeng;  Liu, Tingting;  Wang, Beilei;  Gao, Yuqi;  Liu, Pan
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11
Transglutaminase 3 promotes skin inflammation in atopic dermatitis by activating monocyte-derived dendritic cells via DC-SIGN 期刊论文
2019
作者:  Su Huichun;  Luo Yang;  Sun Jing;  Liu Xiaochun;  Ling Shiqi
收藏  |  浏览/下载：18/0  |  提交时间：2020/01/03
p53-dependent upregulation of miR-16-2 by sanguinarine induces cell cycle arrest and apoptosis in hepatocellular carcinoma 期刊论文
CANCER LETTERS, 2019, 卷号: 459, 页码: 50-58
作者:  Zhang, Beilei;  Wang, Xinan;  Deng, Jiacong;  Zheng, Haifeng;  Liu, Wei
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/30

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