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CORC

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Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan
收藏  |  浏览/下载：94/0  |  提交时间：2020/07/01
KinomeX: a web application for predicting kinome-wide polypharmacology effect of small molecules 期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 24, 页码: 5354-5356
作者:  Li, Zhaojun;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun;  Xiong, Zhaoping
收藏  |  浏览/下载：79/0  |  提交时间：2020/07/01
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models 期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:  Liao, Ping;  Qiu, Yunguang;  Mo, Yiqing;  Fu, Jie;  Song, Zhenpeng
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01
Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 21
作者:  Chen, Deheng;  Lu, Tian;  Yan, Ziqin;  Lu, Wenchao;  Lyu, Xilin
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:  Wu, Chenglin;  Xi, Cong;  Tong, Junhua;  Zhao, Jing;  Jiang, Hualiang
收藏  |  浏览/下载：46/0  |  提交时间：2020/07/01
Dynamic modifications of biomacromolecules: mechanism and chemical interventions 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1459-1471
作者:  Wang, Chu;  Zou, Peng;  Yang, Caiguang;  Liu, Lei;  Cheng, Liang
收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01
High-resolution mapping of brain vasculature and its impairment in the hippocampus of Alzheimer's disease mice 期刊论文
NATIONAL SCIENCE REVIEW, 2019, 卷号: 6, 期号: 6, 页码: 1223-1238
作者:  Zhang, Xiaochuan;  Yin, Xianzhen;  Zhang, Jingjing;  Li, Anan;  Gong, Hui
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01
Nature brings new avenues to the therapy of central nervous system diseases-An overview of possible treatments derived from natural products 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2019, 卷号: 62, 期号: 10, 页码: 1332-1367
作者:  Zhang, Junchi;  He, Yang;  Jiang, Xiangrui;  Jiang, Hualiang;  Shen, Jingshan
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Improving the Virtual Screening Ability of Target-Specific Scoring Functions Using Deep Learning Methods 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 11
作者:  Wang, Dingyan;  Cui, Chen;  Ding, Xiaoyu;  Xiong, Zhaoping;  Zheng, Mingyue
收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01

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