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浏览/检索结果: 共4条，第1-4条 帮助 限定条件 发表日期：2019    专题：中国医学科学院 北京协和医学院    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文 2019, 卷号: 212, 页码: 36-53 作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun 收藏  |  浏览/下载：26/0  |  提交时间：2020/01/03 ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator   IMM-H004 Protects against Cerebral Ischemia Injury and Cardiopulmonary Complications via CKLF1 Mediated Inflammation Pathway in Adult and Aged Rats 期刊论文 2019, 卷号: 20, 期号: 7 作者:  Ai, Qidi;  Chen, Chen;  Chu, Shifeng;  Luo, Yun;  Zhang, Zhao 收藏  |  浏览/下载：7/0  |  提交时间：2020/01/03 IMM-H004  cerebral ischemia  complication  CKLF1  inflammation  aged rats   A20 as a novel target for the anti-neuroinflammatory effect of chrysin via inhibition of NF-kappa B signaling pathway 期刊论文 2019, 卷号: 79, 页码: 228-235 作者:  Li, Zhipeng;  Chu, Shifeng;  He, Wenbin;  Zhang, Zhao;  Liu, Jiaqi 收藏  |  浏览/下载：2/0  |  提交时间：2020/01/03 Chrysin  Neuroinflammation  NF-kappa B  A20  TRAF6   IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization 期刊论文 2019, 卷号: 70, 页码: 69-79 作者:  Chen, Chen;  Ai, Qidi;  Chu, Shifeng;  Zhang, Zhao;  Zhou, Xin 收藏  |  浏览/下载：6/0  |  提交时间：2020/01/03 IMM-H004  CKLF1  BV2 microglia  OGD/R  Microglia polarization