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科研机构
上海药物研究所 [17]
内容类型
期刊论文 [17]
发表日期
2019 [17]
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共17条,第1-10条
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发表日期:2019
专题:上海药物研究所
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Celamonols A-D, four triterpenoid and catechin conjugates with immunosuppressive activities from the stems of Celastrus monospermus
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 22, 页码: 3786-3792
作者:
Qin, Jun-Jun
;
Fu, Yi-Fan
;
Chen, Xi
;
Liu, Yu-Ting
;
Zhao, Ji-Hui
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 14
作者:
Shi, Yulin
;
Fan, Songqing
;
Wu, Mengge
;
Zuo, Zhixiang
;
Li, Xingyang
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/07/01
Organo-Catalyzed Asymmetric Amination of 4-Arylisoquinoline-1,3(2H,4H)-dione Derivatives in the Construction of Quaternary Stereocenters
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2019, 页码: 6
作者:
Cheng, Cheng
;
Li, Ying-Xian
;
Zhang, Ji-Quan
;
Zhao, Yong-Long
;
Zhang, Lin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Isoquinoline-1,3(2H,4H)-dione
Amination reaction
Asymmetric catalysis
Bifunctional catalyst
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
Exploration of the structure-activity relationship and druggability of novel oxazolidinone-based compounds as Gram-negative antibacterial agents
期刊论文
ARCHIV DER PHARMAZIE, 2019, 页码: 13
作者:
Ding, Shi
;
Ji, Jing-Chao
;
Zhang, Ming-Juan
;
Yang, Yu-She
;
Wang, Rui
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
antibacterial activity
oxazolidine
QSAR
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:
Zhou, Ting-ting
;
Zhao, Tong
;
Ma, Fei
;
Zhang, Yi-nan
;
Jiang, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
type 2 diabetes mellitus
hepatic gluconeogenesis
AMPK signaling pathway
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
prodrug
Procyanidin C1, a Component of Cinnamon Extracts, Is a Potential Insulin Sensitizer That Targets Adipocytes
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 32, 页码: 8839-8846
作者:
Sun, Peng
;
Li, Kai
;
Wang, Ting
;
Ji, Jun
;
Wang, Yan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
cinnamon extracts
B-type procyanidin
3T3-L1 adipocytes
insulin sensitivity
glucose uptake
Modelling liver cancer initiation with organoids derived from directly reprogrammed human hepatocytes
期刊论文
NATURE CELL BIOLOGY, 2019, 卷号: 21, 期号: 8, 页码: 1015-+
作者:
Sun, Lulu
;
Wang, Yuqing
;
Cen, Jin
;
Ma, Xiaolong
;
Cui, Lei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis
期刊论文
NATURE, 2019, 卷号: 571, 期号: 7763, 页码: 127-+
作者:
Wang, Xiongjun
;
Liu, Ruilong
;
Zhu, Wencheng
;
Chu, Huiying
;
Yu, Hua
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Simultaneous determination of resibufogenin and its eight metabolites in rat plasma by LC-MS/MS for metabolic profiles and pharmacokinetic study
期刊论文
PHYTOMEDICINE, 2019, 卷号: 60, 页码: 7
作者:
Wei, Wen-long
;
An, Ya-ling
;
Li, Zhen-wei
;
Wang, Ying-ying
;
Ji, Hong-jian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Resibufogenin
Metabolites
Quantitation
Pharmacokinetics
Metabolic profiles
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