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浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916 作者:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming 收藏  |  浏览/下载：65/0  |  提交时间：2019/12/25 CDK9  Kinase inhibitor  Structure-activity relationship  Leukemia   Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846 作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli 收藏  |  浏览/下载：13/0  |  提交时间：2019/12/10 PI3K delta  Kinase inhibitor  Acute myeloid leukemia  Structure-activity relationship   Polarized M2c macrophages have a promoting effect on the epithelial-to-mesenchymal transition of human renal tubular epithelial cells. 期刊论文 Immunobiology, 2018, 卷号: 223, 页码: 826-833 作者:  Chen Zhao;  Dong Fengming;  Lu Jiamei;  Wei Linting;  Tian Lifang 收藏  |  浏览/下载：15/0  |  提交时间：2019/11/26 Epithelial-to-mesenchymal transition (EMT)  Renal tubular epithelial cell  Renal fibrosis  Macrophage   Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor 期刊论文 European Journal of Medicinal Chemistry, 2018, 卷号: Vol.156, 页码: 831-846 作者:  Zongru Jiang;  Wenliang Wang;  Fengming Zou;  Jing Liu;  Qingsong Liu 收藏  |  浏览/下载：7/0  |  提交时间：2019/04/22 PI3Kδ  Kinase  inhibitor  Acute  myeloid  leukemia  Structure-activity  relationship   Discovery of 4--4-amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.158, 页码: 896-916 作者:  Wang, Beilei;  Wu, Yun;  Liu, Qingwang;  Jiang, Zongru;  Wu, Jiaxin 收藏  |  浏览/下载：8/0  |  提交时间：2019/04/24 CDK9  Kinase  inhibitor  Structure-activity  relationship  Leukemia