QQ客服 官方微博 反馈留言

浏览/检索结果: 共10条，第1-10条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction 期刊论文 European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 597-609 作者:  Chen, Danqi;  Chen, Yuehong;  Lian, Fulin;  Chen, Liu;  Li, Yanlian 收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08 Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文 European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689 作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao 收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08 Efficient syntheses of alpha- and beta-C-nucleosides and the origin of anomeric selectivity 期刊论文 ORGANIC CHEMISTRY FRONTIERS, 2018, 卷号: 5, 期号: 12, 页码: 1992-1999 作者:  Liu, Tongchao;  Zhu, Zhengdan;  Ren, Huanming;  Chen, Yabin;  Chen, Guohua 收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 页码: 156-175 作者:  Hu, Jianping;  Wang, Yingqing;  Li, Yanlian;  Cao, Danyan;  Xu, Lin 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 BRD4  BI2536  Indoline  WPF binders  c-Myc  PD-L1   Molecular Modeling Studies on Carbazole Carboxamide Based BTK Inhibitors Using Docking and Structure-Based 3D-QSAR 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 4 作者:  Li, Rui;  Du, Yongli;  Gao, Zhipei;  Shen, Jingkang 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 rheumatoid arthritis (RA)  Broton's tyrosine kinase (BTK)  carbazole carboxamide derivatives  3D-QSAR  comparative molecular field analysis (CoMFA)  comparative molecular similarity indices analysis (CoMSIA)   Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models 期刊论文 MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 期号: 4, 页码: 751-762 作者:  Ai, Jing;  Chen, Yi;  Peng, Xia;  Ji, Yinchun;  Xi, Yong 收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors 期刊论文 MOLECULES, 2018, 卷号: 23, 期号: 3 作者:  Jiang, Alan;  Liu, Qiufeng;  Wang, Ruifeng;  Wei, Peng;  Dai, Yang 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 cancer  FGFR  kinase inhibitor  pyrrolo[2,3-b]pyrazine   Convenient preparation of pinometostat and related 5 '-deoxy-5 '-amino adenosine derivatives as well as their activity against DOT1L 期刊论文 TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 4, 页码: 415-417 作者:  Liu, Tongchao;  Ren, Huanming;  Li, Cong;  Chen, Guohua;  Cheng, Maosheng 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 DOTI L inhibitor  Pinometostat  Amination  5 '-Deoxy-5 '-amino adenosine derivative  Structure activity relationship   Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 692-700 作者:  Du, Yongli;  Zhang, Yanhui;  Ling, Hao;  Li, Qunyi;  Shen, Jingkang 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B inhibitors  N-(2,5-diethoxy-phenyl)-methane sulfonamide  Type 2 diabetes mellitus  PTP1B   Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144 作者:  Du, Yongli;  Zhang, Yanhui;  Ling, Hao;  Li, Qunyi;  Shen, Jingkang 收藏  |  浏览/下载：10/0  |  提交时间：2019/12/05 Protein tyrosine phosphatase 1B inhibitors  N-(2,5-diethoxy-phenyl)-methane sulfonamide  Type 2 diabetes mellitus  PTP1B